Aripiprazole [Usan]
Brand names,
Aripiprazole [Usan]
Analogs
Aripiprazole [Usan]
Brand Names Mixture
Aripiprazole [Usan]
Chemical_Formula
C23H27Cl2N3O2
Aripiprazole [Usan]
RX_link
http://www.rxlist.com/cgi/generic/abilify.htm
Aripiprazole [Usan]
fda sheet
Aripiprazole [Usan]
msds (material safety sheet)
Aripiprazole [Usan]
Synthesis Reference
No information avaliable
Aripiprazole [Usan]
Molecular Weight
448.385 g/mol
Aripiprazole [Usan]
Melting Point
No information avaliable
Aripiprazole [Usan]
H2O Solubility
No information avaliable
Aripiprazole [Usan]
State
Solid
Aripiprazole [Usan]
LogP
4.537
Aripiprazole [Usan]
Dosage Forms
No information avaliable
Aripiprazole [Usan]
Indication
For the treatment of schizophrenia
Aripiprazole [Usan]
Pharmacology
Aripiprazole is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives and is indicated for the treatment of schizophrenia. Aripiprazole is a selective monoaminergic antagonist with high affinity for the serotonin Type 2 (5HT2), dopamine Type 2 (D2), 1 and 2 adrenergic, and H1 histaminergic receptors. Aripiprazole acts as an antagonist at other receptors, but with lower potency. Antagonism at receptors other than dopamine and 5HT2 with similar receptor affinities may explain some of the other therapeutic and side effects of Aripiprazole. Aripiprazole's antagonism of histamine H1 receptors may explain the somnolence observed with this drug. Aripiprazole's antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug.
Aripiprazole [Usan]
Absorption
No information avaliable
Aripiprazole [Usan]
side effects and Toxicity
No information avaliable
Aripiprazole [Usan]
Patient Information
Aripiprazole [Usan]
Organisms Affected
Humans and other mammals