Abilify
Brand names,
Abilify
Analogs
Abilify
Brand Names Mixture
Abilify
Chemical_Formula
C23H27Cl2N3O2
Abilify
RX_link
http://www.rxlist.com/cgi/generic/abilify.htm
Abilify
fda sheet
Abilify
msds (material safety sheet)
Abilify
Synthesis Reference
No information avaliable
Abilify
Molecular Weight
448.385 g/mol
Abilify
Melting Point
No information avaliable
Abilify
H2O Solubility
No information avaliable
Abilify
State
Solid
Abilify
LogP
4.537
Abilify
Dosage Forms
No information avaliable
Abilify
Indication
For the treatment of schizophrenia
Abilify
Pharmacology
Aripiprazole is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives and is indicated for the treatment of schizophrenia. Aripiprazole is a selective monoaminergic antagonist with high affinity for the serotonin Type 2 (5HT2), dopamine Type 2 (D2), 1 and 2 adrenergic, and H1 histaminergic receptors. Aripiprazole acts as an antagonist at other receptors, but with lower potency. Antagonism at receptors other than dopamine and 5HT2 with similar receptor affinities may explain some of the other therapeutic and side effects of Aripiprazole. Aripiprazole's antagonism of histamine H1 receptors may explain the somnolence observed with this drug. Aripiprazole's antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug.
Abilify
Absorption
No information avaliable
Abilify
side effects and Toxicity
No information avaliable
Abilify
Patient Information
Abilify
Organisms Affected
Humans and other mammals