Abilitat
Brand names,
Abilitat
Analogs
Abilitat
Brand Names Mixture
Abilitat
Chemical_Formula
C23H27Cl2N3O2
Abilitat
RX_link
http://www.rxlist.com/cgi/generic/abilify.htm
Abilitat
fda sheet
Abilitat
msds (material safety sheet)
Abilitat
Synthesis Reference
No information avaliable
Abilitat
Molecular Weight
448.385 g/mol
Abilitat
Melting Point
No information avaliable
Abilitat
H2O Solubility
No information avaliable
Abilitat
State
Solid
Abilitat
LogP
4.537
Abilitat
Dosage Forms
No information avaliable
Abilitat
Indication
For the treatment of schizophrenia
Abilitat
Pharmacology
Aripiprazole is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives and is indicated for the treatment of schizophrenia. Aripiprazole is a selective monoaminergic antagonist with high affinity for the serotonin Type 2 (5HT2), dopamine Type 2 (D2), 1 and 2 adrenergic, and H1 histaminergic receptors. Aripiprazole acts as an antagonist at other receptors, but with lower potency. Antagonism at receptors other than dopamine and 5HT2 with similar receptor affinities may explain some of the other therapeutic and side effects of Aripiprazole. Aripiprazole's antagonism of histamine H1 receptors may explain the somnolence observed with this drug. Aripiprazole's antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug.
Abilitat
Absorption
No information avaliable
Abilitat
side effects and Toxicity
No information avaliable
Abilitat
Patient Information
Abilitat
Organisms Affected
Humans and other mammals