Almotriptan
Almotriptan Brand names, Almotriptan Analogs
Almotriptan Brand Names Mixture
- No information avaliable
Almotriptan Chemical_Formula
C17H25N3O2S
Almotriptan RX_link
http://www.rxlist.com/cgi/generic2/almotriptan.htm
Almotriptan fda sheet
Almotriptan msds (material safety sheet)
Almotriptan Synthesis Reference
No information avaliable
Almotriptan Molecular Weight
335.465 g/mol
Almotriptan Melting Point
No information avaliable
Almotriptan H2O Solubility
No information avaliable
Almotriptan State
Solid
Almotriptan LogP
1.87
Almotriptan Dosage Forms
Tablet
Almotriptan Indication
For the treatment of acute migraine headache in adults
Almotriptan Pharmacology
Almotriptan is a selective 5-hydroxytryptamine receptor subtype agonist indicated for the acute treatment of migraine attacks with or without aura in adults. Almotriptan is not intended for the prophylactic therapy of migraine or for use in the management of hemiplegic or basilar migraine. Almotriptan is an agonist for a vascular 5-hydroxytryptamine receptor subtype (probably a member of the 5-HT1D family) having only a weak affinity for 5-HT1A, 5-HT5A, and 5-HT7 receptors and no significant affinity or pharmacological activity at 5-HT2, 5-HT3 or 5-HT4 receptor subtypes or at alpha1-, alpha2-, or beta-adrenergic, dopamine1,; dopamine2; muscarinic, or benzodiazepine receptors. This action in humans correlates with the relief of migraine headache. In addition to causing vasoconstriction, experimental data from animal studies show that Almotriptan also activates 5-HT1 receptors on peripheral terminals of the trigeminal nerve innervating cranial blood vessels, which may also contribute to the antimigrainous effect of Almotriptan in humans.
Almotriptan Absorption
No information avaliable
Almotriptan side effects and Toxicity
No information avaliable
Almotriptan Patient Information
No information avaliable
Almotriptan Organisms Affected
Humans and other mammals
