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Aladerm Brand names, Aladerm Analogs

Aladerm Brand Names Mixture

  • No information avaliable

Aladerm Chemical_Formula


Aladerm RX_link

Aladerm fda sheet

Aladerm FDA

Aladerm msds (material safety sheet)

Aladerm MSDS

Aladerm Synthesis Reference

No information avaliable

Aladerm Molecular Weight

131.13 g/mol

Aladerm Melting Point

156-158 oC

Aladerm H2O Solubility

Very soluble

Aladerm State


Aladerm LogP


Aladerm Dosage Forms

Two component system consisting of a plastic tube containing two sealed glass ampules and an applicator tip (one ampule contains 1.5 mL of solution vehicle, the other ampule contains 354 mg of aminolevulinic acid hcl as a dry solid)

Aladerm Indication

Aminolevulinic acid plus blue light illumination using a blue light photodynamic therapy illuminator is indicated for the treatment of minimally to moderately thick actinic keratoses of the face or scalp.

Aladerm Pharmacology

The metabolism of aminolevulinic acid (ALA) is the first step in the biochemical pathway resulting in heme synthesis. Aminolevulinic acid is not a photosensitizer, but rather a metabolic precursor of protoporphyrin IX (PpIX), which is a photosensitizer. The synthesis of ALA is normally tightly controlled by feedback inhibition of the enzyme, ALA synthetase, presumably by intracellular heme levels. ALA, when provided to the cell, bypasses this control point and results in the accumulation of PpIX, which is converted into heme by ferrochelatase through the addition of iron to the PpIX nucleus.

Aladerm Absorption

Oral bioavailability is 50-60%.

Aladerm side effects and Toxicity

Solution overdose have not been reported.

Aladerm Patient Information

Aladerm Organisms Affected

Humans and other mammals