Aircrit

Aircrit Brand names, Aircrit Analogs

Aircrit Brand Names Mixture

Tenoretic (atenolol + chlorthalidone)

Aircrit Chemical_Formula

C₁₄H₂₂N₂O₃

Aircrit RX_link

http://www.rxlist.com/cgi/generic/atenolol.htm

Aircrit fda sheet

Aircrit msds (material safety sheet)

Aircrit Synthesis Reference

Barrett et al., U.S. Pat. 3,,663,607 (1972)

Aircrit Molecular Weight

266.336 g/mol

Aircrit Melting Point

146-148^oC

Aircrit H₂O Solubility

13.5 mg/mL

Aircrit State

Solid

Aircrit LogP

1.256

Aircrit Dosage Forms

Tablet (25, 50 and 100 mg); Intravenous injection

Aircrit Indication

For the management of hypertention and long-term management of patients with angina pectoris

Aircrit Pharmacology

Atenolol, a competitive beta(1)-selective adrenergic antagonist, has the lowest lipid solubility of this drug class. Although it is similar to metoprolol, atenolol differs from pindolol and propranolol in that it does not have intrinsic sympathomimetic properties or membrane-stabilizing activity. Atenolol is used alone or with chlorthalidone in the management of hypertension and edema.

Aircrit Absorption

oral dose if rapid and consisten but incomplete. Approximately 50% of an oral dose is absorbed from the gastrointestinal tract, the remainder being excreted unchanged in the feces.

Aircrit side effects and Toxicity

LD₅₀=2000-3000 mg/kg(orally in mice). Symptoms of an atenolol overdose include a slow heart beat, shortness of breath, fainting, dizziness, weakness, confusion, nausea, and vomiting.

Aircrit Patient Information

This belongs to the group of medicines known as beta-blockers. Atenolol can
be used to treat high blood pressure, angina (chest pain) and irregular
heartbeat. It has varied effects in different parts of the body. High Blood
Pressure: Atenolol works by blocking the transmission of messages to the beta
receptors in the heart which slows down the activity of the heart, decreasing
blood pressure. Angina: Atenolol works by blocking the transmission of messages
to the beta receptors in the heart which slows down the activity of the heart
and reduces the heart's need for oxygen. This makes angina attacks less likely
to occur. Irregular Heartbeat: Normally the heartbeat is regulated by special
tissues which conduct electricity. Some cases of irregular heartbeat are caused
by these tissues conducting electricity too quickly. Atenolol works by reducing
over-activity in the conducting tissue.

Aircrit Organisms Affected

Humans and other mammals