Agalsidase alfa
Agalsidase alfa Brand names, Agalsidase alfa Analogs
Agalsidase alfa Brand Names Mixture
- No information avaliable
Agalsidase alfa Chemical_Formula
C2029H3080N544O587S27
Agalsidase alfa RX_link
http://www.rxlist.com/cgi/generic3/fabrazyme.htm
Agalsidase alfa fda sheet
Agalsidase alfa msds (material safety sheet)
Agalsidase alfa Synthesis Reference
No information avaliable
Agalsidase alfa Molecular Weight
45351.6
Agalsidase alfa Melting Point
No information avaliable
Agalsidase alfa H2O Solubility
No information avaliable
Agalsidase alfa State
Liquid
Agalsidase alfa LogP
-0.307
Agalsidase alfa Dosage Forms
Powder for solution
Agalsidase alfa Indication
For treatment of Fabry's disease (alpha-galactosidase A deficiency)
Agalsidase alfa Pharmacology
Used in the treatment of Fabry disease, an X-linked genetic disorder of glycosphingolipid metabolism. The disease is characterized by a deficiency of the lysosomal enzyme alpha-galactosidase A, which leads to progressive accumulation of glycosphingolipids, predominantly GL-3, in many body tissues. Clinical manifestations of Fabry disease include renal failure, cardiomyopathy, and cerebrovascular accidents. Fabrazyme is intended to provide an exogenous source of alpha-galactosidase A and to limit the accumulation of these glycolipids in the tissues.
Agalsidase alfa Absorption
No information avaliable
Agalsidase alfa side effects and Toxicity
No information avaliable
Agalsidase alfa Patient Information
BIOD00075.html
Agalsidase alfa Organisms Affected
Humans and other mammals
