Alpha-galactosidase A precursor
Brand names,
Alpha-galactosidase A precursor
Analogs
Alpha-galactosidase A precursor
Brand Names Mixture
Alpha-galactosidase A precursor
Chemical_Formula
C2029H3080N544O587S27
Alpha-galactosidase A precursor
RX_link
http://www.rxlist.com/cgi/generic3/fabrazyme.htm
Alpha-galactosidase A precursor
fda sheet
Alpha-galactosidase A precursor
msds (material safety sheet)
Alpha-galactosidase A precursor
Synthesis Reference
No information avaliable
Alpha-galactosidase A precursor
Molecular Weight
45351.6
Alpha-galactosidase A precursor
Melting Point
No information avaliable
Alpha-galactosidase A precursor
H2O Solubility
No information avaliable
Alpha-galactosidase A precursor
State
Liquid
Alpha-galactosidase A precursor
LogP
-0.307
Alpha-galactosidase A precursor
Dosage Forms
Powder for solution
Alpha-galactosidase A precursor
Indication
For treatment of Fabry's disease (alpha-galactosidase A deficiency)
Alpha-galactosidase A precursor
Pharmacology
Used in the treatment of Fabry disease, an X-linked genetic disorder of glycosphingolipid metabolism. The disease is characterized by a deficiency of the lysosomal enzyme alpha-galactosidase A, which leads to progressive accumulation of glycosphingolipids, predominantly GL-3, in many body tissues. Clinical manifestations of Fabry disease include renal failure, cardiomyopathy, and cerebrovascular accidents. Fabrazyme is intended to provide an exogenous source of alpha-galactosidase A and to limit the accumulation of these glycolipids in the tissues.
Alpha-galactosidase A precursor
Absorption
No information avaliable
Alpha-galactosidase A precursor
side effects and Toxicity
No information avaliable
Alpha-galactosidase A precursor
Patient Information
BIOD00075.html
Alpha-galactosidase A precursor
Organisms Affected
Humans and other mammals