Melibiase
Brand names,
Melibiase
Analogs
Melibiase
Brand Names Mixture
Melibiase
Chemical_Formula
C2029H3080N544O587S27
Melibiase
RX_link
http://www.rxlist.com/cgi/generic3/fabrazyme.htm
Melibiase
fda sheet
Melibiase
msds (material safety sheet)
Melibiase
Synthesis Reference
No information avaliable
Melibiase
Molecular Weight
45351.6
Melibiase
Melting Point
No information avaliable
Melibiase
H2O Solubility
No information avaliable
Melibiase
State
Liquid
Melibiase
LogP
-0.307
Melibiase
Dosage Forms
Powder for solution
Melibiase
Indication
For treatment of Fabry's disease (alpha-galactosidase A deficiency)
Melibiase
Pharmacology
Used in the treatment of Fabry disease, an X-linked genetic disorder of glycosphingolipid metabolism. The disease is characterized by a deficiency of the lysosomal enzyme alpha-galactosidase A, which leads to progressive accumulation of glycosphingolipids, predominantly GL-3, in many body tissues. Clinical manifestations of Fabry disease include renal failure, cardiomyopathy, and cerebrovascular accidents. Fabrazyme is intended to provide an exogenous source of alpha-galactosidase A and to limit the accumulation of these glycolipids in the tissues.
Melibiase
Absorption
No information avaliable
Melibiase
side effects and Toxicity
No information avaliable
Melibiase
Patient Information
BIOD00075.html
Melibiase
Organisms Affected
Humans and other mammals