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Topotecan Brand names, Topotecan Analogs

Topotecan Brand Names Mixture

  • No information avaliable

Topotecan Chemical_Formula


Topotecan RX_link

Topotecan fda sheet

Topotecan FDA

Topotecan msds (material safety sheet)

Topotecan MSDS

Topotecan Synthesis Reference

No information avaliable

Topotecan Molecular Weight

421.446 g/mol

Topotecan Melting Point

213-218 oC

Topotecan H2O Solubility

1 mg/ml

Topotecan State


Topotecan LogP


Topotecan Dosage Forms

Powder for solution

Topotecan Indication

For the treatment of metastatic carcinoma of the ovary and small cell lung cancer following the failure of first-line chemotherapy.

Topotecan Pharmacology

Topotecan, a semi-synthetic derivative of camptothecin (a plant alkaloid obtained from the Camptotheca acuminata tree), is an anti-tumor drug with topoisomerase I-inhibitory activity similar to irinotecan. Topotecan interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal cells may also be affected by the medicine, other effects may also occur. Unlike irinotecan, topotecan is found predominantly in the inactive carboxylate form at neutral pH and it is not a prodrug.

Topotecan Absorption

No information avaliable

Topotecan side effects and Toxicity

The primary anticipated complication of overdosage would consist of bone marrow suppression.

Topotecan Patient Information

No information avaliable

Topotecan Organisms Affected

Humans and other mammals