PharmacyCodes



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TTC Brand names, TTC Analogs

TTC Brand Names Mixture

  • No information avaliable

TTC Chemical_Formula

C23H23N3O5

TTC RX_link

http://www.rxlist.com/cgi/generic2/topotec.htm

TTC fda sheet

TTC FDA

TTC msds (material safety sheet)

TTC MSDS

TTC Synthesis Reference

No information avaliable

TTC Molecular Weight

421.446 g/mol

TTC Melting Point

213-218 oC

TTC H2O Solubility

1 mg/ml

TTC State

Solid

TTC LogP

1.21

TTC Dosage Forms

Powder for solution

TTC Indication

For the treatment of metastatic carcinoma of the ovary and small cell lung cancer following the failure of first-line chemotherapy.

TTC Pharmacology

Topotecan, a semi-synthetic derivative of camptothecin (a plant alkaloid obtained from the Camptotheca acuminata tree), is an anti-tumor drug with topoisomerase I-inhibitory activity similar to irinotecan. Topotecan interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal cells may also be affected by the medicine, other effects may also occur. Unlike irinotecan, topotecan is found predominantly in the inactive carboxylate form at neutral pH and it is not a prodrug.

TTC Absorption

No information avaliable

TTC side effects and Toxicity

The primary anticipated complication of overdosage would consist of bone marrow suppression.

TTC Patient Information

No information avaliable

TTC Organisms Affected

Humans and other mammals