Methoxane
Category
Methoxane Brand names, Methoxane Analogs
Methoxane Brand Names Mixture
Methoxane Chemical_Formula
C3H4Cl2F2O
Methoxane RX_link
No information avaliable
Methoxane fda sheet
Methoxane msds (material safety sheet)
Methoxane Synthesis Reference
Miller et al., J. Am. Chem. Soc. 70, 431 (1948)
Methoxane Molecular Weight
164.965 g/mol
Methoxane Melting Point
-35 oC (melting point), 105 oC (boiling point)
Methoxane H2O Solubility
2.83E+004 mg/L
Methoxane State
Liquid
Methoxane LogP
2.073
Methoxane Dosage Forms
Spray
Methoxane Indication
For use in the induction and maintenance of general anesthesia
Methoxane Pharmacology
Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Methoxane Absorption
No information avaliable
Methoxane side effects and Toxicity
LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.
Methoxane Patient Information
No information avaliable
Methoxane Organisms Affected
Humans and other mammals
