Methoxyfluorane
Methoxyfluorane Brand names, Methoxyfluorane Analogs
Methoxyfluorane Brand Names Mixture
- No information avaliable
Methoxyfluorane Chemical_Formula
C3H4Cl2F2O
Methoxyfluorane RX_link
No information avaliable
Methoxyfluorane fda sheet
Methoxyfluorane msds (material safety sheet)
Methoxyfluorane Synthesis Reference
Miller et al., J. Am. Chem. Soc. 70, 431 (1948)
Methoxyfluorane Molecular Weight
164.965 g/mol
Methoxyfluorane Melting Point
-35 oC (melting point), 105 oC (boiling point)
Methoxyfluorane H2O Solubility
2.83E+004 mg/L
Methoxyfluorane State
Liquid
Methoxyfluorane LogP
2.073
Methoxyfluorane Dosage Forms
Spray
Methoxyfluorane Indication
For use in the induction and maintenance of general anesthesia
Methoxyfluorane Pharmacology
Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Methoxyfluorane Absorption
No information avaliable
Methoxyfluorane side effects and Toxicity
LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.
Methoxyfluorane Patient Information
No information avaliable
Methoxyfluorane Organisms Affected
Humans and other mammals
