MOF
MOF Brand names, MOF Analogs
MOF Brand Names Mixture
- No information avaliable
MOF Chemical_Formula
C3H4Cl2F2O
MOF RX_link
No information avaliable
MOF fda sheet
MOF msds (material safety sheet)
MOF Synthesis Reference
Miller et al., J. Am. Chem. Soc. 70, 431 (1948)
MOF Molecular Weight
164.965 g/mol
MOF Melting Point
-35 oC (melting point), 105 oC (boiling point)
MOF H2O Solubility
2.83E+004 mg/L
MOF State
Liquid
MOF LogP
2.073
MOF Dosage Forms
Spray
MOF Indication
For use in the induction and maintenance of general anesthesia
MOF Pharmacology
Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
MOF Absorption
No information avaliable
MOF side effects and Toxicity
LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.
MOF Patient Information
No information avaliable
MOF Organisms Affected
Humans and other mammals
