Methofane
Methofane Brand names, Methofane Analogs
Methofane Brand Names Mixture
- No information avaliable
Methofane Chemical_Formula
C3H4Cl2F2O
Methofane RX_link
No information avaliable
Methofane fda sheet
Methofane msds (material safety sheet)
Methofane Synthesis Reference
Miller et al., J. Am. Chem. Soc. 70, 431 (1948)
Methofane Molecular Weight
164.965 g/mol
Methofane Melting Point
-35 oC (melting point), 105 oC (boiling point)
Methofane H2O Solubility
2.83E+004 mg/L
Methofane State
Liquid
Methofane LogP
2.073
Methofane Dosage Forms
Spray
Methofane Indication
For use in the induction and maintenance of general anesthesia
Methofane Pharmacology
Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Methofane Absorption
No information avaliable
Methofane side effects and Toxicity
LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.
Methofane Patient Information
No information avaliable
Methofane Organisms Affected
Humans and other mammals
