Metoxfluran
Category
Metoxfluran Brand names, Metoxfluran Analogs
Metoxfluran Brand Names Mixture
Metoxfluran Chemical_Formula
C3H4Cl2F2O
Metoxfluran RX_link
No information avaliable
Metoxfluran fda sheet
Metoxfluran msds (material safety sheet)
Metoxfluran Synthesis Reference
Miller et al., J. Am. Chem. Soc. 70, 431 (1948)
Metoxfluran Molecular Weight
164.965 g/mol
Metoxfluran Melting Point
-35 oC (melting point), 105 oC (boiling point)
Metoxfluran H2O Solubility
2.83E+004 mg/L
Metoxfluran State
Liquid
Metoxfluran LogP
2.073
Metoxfluran Dosage Forms
Spray
Metoxfluran Indication
For use in the induction and maintenance of general anesthesia
Metoxfluran Pharmacology
Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Metoxfluran Absorption
No information avaliable
Metoxfluran side effects and Toxicity
LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.
Metoxfluran Patient Information
No information avaliable
Metoxfluran Organisms Affected
Humans and other mammals
