Penthrane
Penthrane Brand names, Penthrane Analogs
Penthrane Brand Names Mixture
- No information avaliable
Penthrane Chemical_Formula
C3H4Cl2F2O
Penthrane RX_link
No information avaliable
Penthrane fda sheet
Penthrane msds (material safety sheet)
Penthrane Synthesis Reference
Miller et al., J. Am. Chem. Soc. 70, 431 (1948)
Penthrane Molecular Weight
164.965 g/mol
Penthrane Melting Point
-35 oC (melting point), 105 oC (boiling point)
Penthrane H2O Solubility
2.83E+004 mg/L
Penthrane State
Liquid
Penthrane LogP
2.073
Penthrane Dosage Forms
Spray
Penthrane Indication
For use in the induction and maintenance of general anesthesia
Penthrane Pharmacology
Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Penthrane Absorption
No information avaliable
Penthrane side effects and Toxicity
LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.
Penthrane Patient Information
No information avaliable
Penthrane Organisms Affected
Humans and other mammals
