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Aminokapron Brand names, Aminokapron Analogs

Aminokapron Brand Names Mixture

  • No information avaliable

Aminokapron Chemical_Formula


Aminokapron RX_link

Aminokapron fda sheet

Aminokapron FDA

Aminokapron msds (material safety sheet)

Aminokapron MSDS

Aminokapron Synthesis Reference

No information avaliable

Aminokapron Molecular Weight

131.173 g/mol

Aminokapron Melting Point

205 oC

Aminokapron H2O Solubility

5.05E+005 mg/L

Aminokapron State


Aminokapron LogP


Aminokapron Dosage Forms

Solution for injection (containing 250 mg/mL of aminocaproic acid) and tablets (500, 1000mg)

Aminokapron Indication

For use in the treatment of excessive postoperative bleeding.

Aminokapron Pharmacology

Aminocaproic acid works as an antifibrinolytic. It is a derivative of the amino acid lysine. The fibrinolysis-inhibitory effects of aminocaproic acid appear to be exerted principally via inhibition of plasminogen activators and to a lesser degree through antiplasmin activity.

Aminokapron Absorption

Absorbed rapidly following oral administration. In adults, oral absorption appears to be a zero-order process with an absorption rate of 5.2 g/hr. The mean lag time in absorption is 10 minutes. After a single oral dose of 5 g, absorption was complete (F=1).

Aminokapron side effects and Toxicity

A few cases of acute overdosage with intravenous administration have been reported. The effects have ranged from no reaction to transient hypotension to severe acute renal failure leading to death. The intravenous and oral LD50 were 3.0 and 12.0 g/kg respectively in the mouse and 3.2 and 16.4 g/kg respectively in the rat. An intravenous infusion dose of 2.3 g/kg was lethal in the dog.

Aminokapron Patient Information

Aminokapron Organisms Affected

Humans and other mammals