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Ipsilon Brand names, Ipsilon Analogs

Ipsilon Brand Names Mixture

  • No information avaliable

Ipsilon Chemical_Formula

C6H13NO2

Ipsilon RX_link

http://www.rxlist.com/cgi/generic/amicarpre.htm

Ipsilon fda sheet

Ipsilon FDA

Ipsilon msds (material safety sheet)

Ipsilon MSDS

Ipsilon Synthesis Reference

No information avaliable

Ipsilon Molecular Weight

131.173 g/mol

Ipsilon Melting Point

205 oC

Ipsilon H2O Solubility

5.05E+005 mg/L

Ipsilon State

Solid

Ipsilon LogP

0.306

Ipsilon Dosage Forms

Solution for injection (containing 250 mg/mL of aminocaproic acid) and tablets (500, 1000mg)

Ipsilon Indication

For use in the treatment of excessive postoperative bleeding.

Ipsilon Pharmacology

Aminocaproic acid works as an antifibrinolytic. It is a derivative of the amino acid lysine. The fibrinolysis-inhibitory effects of aminocaproic acid appear to be exerted principally via inhibition of plasminogen activators and to a lesser degree through antiplasmin activity.

Ipsilon Absorption

Absorbed rapidly following oral administration. In adults, oral absorption appears to be a zero-order process with an absorption rate of 5.2 g/hr. The mean lag time in absorption is 10 minutes. After a single oral dose of 5 g, absorption was complete (F=1).

Ipsilon side effects and Toxicity

A few cases of acute overdosage with intravenous administration have been reported. The effects have ranged from no reaction to transient hypotension to severe acute renal failure leading to death. The intravenous and oral LD50 were 3.0 and 12.0 g/kg respectively in the mouse and 3.2 and 16.4 g/kg respectively in the rat. An intravenous infusion dose of 2.3 g/kg was lethal in the dog.

Ipsilon Patient Information

Ipsilon Organisms Affected

Humans and other mammals