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Hemopar Brand names, Hemopar Analogs

Hemopar Brand Names Mixture

  • No information avaliable

Hemopar Chemical_Formula

C6H13NO2

Hemopar RX_link

http://www.rxlist.com/cgi/generic/amicarpre.htm

Hemopar fda sheet

Hemopar FDA

Hemopar msds (material safety sheet)

Hemopar MSDS

Hemopar Synthesis Reference

No information avaliable

Hemopar Molecular Weight

131.173 g/mol

Hemopar Melting Point

205 oC

Hemopar H2O Solubility

5.05E+005 mg/L

Hemopar State

Solid

Hemopar LogP

0.306

Hemopar Dosage Forms

Solution for injection (containing 250 mg/mL of aminocaproic acid) and tablets (500, 1000mg)

Hemopar Indication

For use in the treatment of excessive postoperative bleeding.

Hemopar Pharmacology

Aminocaproic acid works as an antifibrinolytic. It is a derivative of the amino acid lysine. The fibrinolysis-inhibitory effects of aminocaproic acid appear to be exerted principally via inhibition of plasminogen activators and to a lesser degree through antiplasmin activity.

Hemopar Absorption

Absorbed rapidly following oral administration. In adults, oral absorption appears to be a zero-order process with an absorption rate of 5.2 g/hr. The mean lag time in absorption is 10 minutes. After a single oral dose of 5 g, absorption was complete (F=1).

Hemopar side effects and Toxicity

A few cases of acute overdosage with intravenous administration have been reported. The effects have ranged from no reaction to transient hypotension to severe acute renal failure leading to death. The intravenous and oral LD50 were 3.0 and 12.0 g/kg respectively in the mouse and 3.2 and 16.4 g/kg respectively in the rat. An intravenous infusion dose of 2.3 g/kg was lethal in the dog.

Hemopar Patient Information

Hemopar Organisms Affected

Humans and other mammals