Categoria
Lisino
Marchi,
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Analoghi
Lisino
Marchi miscela
Chlor-Tripolon ND SRT (Loratadine + Pseudoephedrine Sulfate) Claritin Allergy + Sinus Extra Strength (Loratadine + Pseudoephedrine Sulfate) Liberator (Loratadine + Pseudoephedrine Sulfate)
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Formula chimica
C22H23ClN2O2
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RX link
http://www.rxlist.com/cgi/generic/lorat.htm
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FDA foglio
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DMS (foglio di materiale di sicurezza)
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Sintesi di riferimento
FJ Villani, US Pat. 4,282,233 (1981)
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Peso molecolare
382.883 g/mol
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Temperatura di fusione
134-136 oC
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H2O Solubilita
0.000011 mg / ml
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Stato
Solid
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LogP
3.646
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Forme di dosaggio
Tablet; Sciroppo
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Indicazione
Per il sollievo dei sintomi nasali e non nasali della rinite allergica stagionale e per il trattamento di orticaria cronica idiopatica in pazienti di 2 anni di età o più anziani
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Farmacologia
Loratadina, un non-sedativo H1-bloccante una struttura simile alla ciproeptadina e azatadine, è usato per curare rinite allergica stagionale. A differenza di altri H1-bloccanti, loratidina non penetra il sistema nervoso centrale in modo efficace e ha una bassa affinità per i recettori H1 sistema nervoso centrale.
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Assorbimento
Rapidamente assorbito dopo somministrazione orale (40% biodisponibilità)
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Tossicita
sonnolenza, tachicardia e mal di testa LD50 = mg / kg (per via orale nel ratto)
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Informazioni paziente
Description
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This medicine is used to treat symptoms of hay fever such as runny nose,
watery eyes and sneezing. Your doctor may use antihistimines for other
conditions as well.
General Information
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This information is for educational purposes only. Not every known side
effect, adverse effect, or drug interaction is in this database. If you
have questions about your medicines, talk to your healthcare provider.
Proper use of this medicine
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For proper use of this medicine, follow the directions on the package,
unless otherwise instructed by your doctor.
Missed Dose
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If your doctor has instructed you to take this medicine regularly and you
miss a dose, take your next dose, as soon as you remember. If you are close
to your next dose, do not double up. Skip the missed dose and go back to
your regular schedule.
Storage
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Keep this medication in the container it came in, tightly closed, and out
of reach of children. Store it at room temperature and away from excess
heat and moisture (not in the bathroom). Throw away any medication that
is outdated or no longer needed.
Possible Side Effects
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Common side effects include:
dizzines
drowsiness
dry mouth
This medicine can cause excitement especially in children.
See a doctor immediately if you experience:
fast or irregular heartbeat
mental or mood changes
tightness in the chest
unusual tiredness or weakness.
While taking this medicine, if you experience, chest tightness, difficulty
in breathing or swallowing, swelling in the face or lips, go to the doctor
immediately and stop taking the medication until you have talked to your
doctor.
Warnings/Precautions
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Do NOT take this medicine with orange, apple or grapefruit juice. The levels
of this medicine in your blood may be decreased by 70%.
Overdose
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Seek medical attention immediately. For non emergencies, contact your local
or regional poison control center
Drug Interactions
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Before taking any other medications, by prescription or over-the-counter
(OTC) talk to your health care provider. Some medicines may change the way
this medicine affects your body. Also the effects of other medicines may
be increased or decreased by this medicine.
Pregnancy/Nursing
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Talk to your doctor about using this medicine during pregnancy or nursing
to discuss any possible risks to you or your baby.
More Information
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For more information about this medicine, talk to your healthcare provider
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Atto interessato organismi
Gli esseri umani e altri mammiferi