Nularef

Nularef Brand names, Nularef Analogs

Nularef Brand Names Mixture

Chlor-Tripolon ND SRT (Loratadine + Pseudoephedrine Sulfate)
Claritin Allergy + Sinus Extra Strength (Loratadine + Pseudoephedrine Sulfate)
Liberator (Loratadine + Pseudoephedrine Sulfate)

Nularef Chemical_Formula

C₂₂H₂₃ClN₂O₂

Nularef RX_link

http://www.rxlist.com/cgi/generic/lorat.htm

Nularef fda sheet

Nularef FDA

Nularef msds (material safety sheet)

Nularef MSDS

Nularef Synthesis Reference

F. J. Villani, U.S. Pat. 4,282,233 (1981)

Nularef Molecular Weight

382.883 g/mol

Nularef Melting Point

134-136 ^oC

Nularef H₂O Solubility

0.000011 mg/ml

Nularef State

Solid

Nularef LogP

3.646

Nularef Dosage Forms

Tablet; Syrup

Nularef Indication

For the relief of nasal and non-nasal symptoms of seasonal allergic rhinitis and for the treatment of chronic idiopathic urticaria in patients 2 years of age or older

Nularef Pharmacology

Loratadine, a non-sedating H₁-blocker similar in structure to cyproheptadine and azatadine, is used to treat seasonal allergic rhinitis. Unlike other H₁-blockers, loratidine does not penetrate the CNS effectively and has a low affinity for CNS H₁-receptors.

Nularef Absorption

Rapidly absorbed following oral administration (40% bioavailability)

Nularef side effects and Toxicity

somnolence, tachycardia, and headache LD₅₀=mg/kg (orally in rat)

Nularef Patient Information

Description
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This medicine is used to treat symptoms of hay fever such as runny nose,
watery eyes and sneezing. Your doctor may use antihistimines for other
conditions as well.

General Information
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This information is for educational purposes only. Not every known side
effect, adverse effect, or drug interaction is in this database. If you
have questions about your medicines, talk to your healthcare provider.

Proper use of this medicine
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For proper use of this medicine, follow the directions on the package,
unless otherwise instructed by your doctor.

Missed Dose
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If your doctor has instructed you to take this medicine regularly and you
miss a dose, take your next dose, as soon as you remember. If you are close
to your next dose, do not double up. Skip the missed dose and go back to
your regular schedule.

Storage
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Keep this medication in the container it came in, tightly closed, and out
of reach of children. Store it at room temperature and away from excess
heat and moisture (not in the bathroom). Throw away any medication that
is outdated or no longer needed.

Possible Side Effects
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Common side effects include:
dizzines
drowsiness
dry mouth
This medicine can cause excitement especially in children.
See a doctor immediately if you experience:
fast or irregular heartbeat
mental or mood changes
tightness in the chest
unusual tiredness or weakness.
While taking this medicine, if you experience, chest tightness, difficulty
in breathing or swallowing, swelling in the face or lips, go to the doctor
immediately and stop taking the medication until you have talked to your
doctor.

Warnings/Precautions
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Do NOT take this medicine with orange, apple or grapefruit juice. The levels
of this medicine in your blood may be decreased by 70%.

Overdose
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Seek medical attention immediately. For non emergencies, contact your local
or regional poison control center

Drug Interactions
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Before taking any other medications, by prescription or over-the-counter
(OTC) talk to your health care provider. Some medicines may change the way
this medicine affects your body. Also the effects of other medicines may
be increased or decreased by this medicine.

Pregnancy/Nursing
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Talk to your doctor about using this medicine during pregnancy or nursing
to discuss any possible risks to you or your baby.

More Information
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For more information about this medicine, talk to your healthcare provider

Nularef Organisms Affected

Humans and other mammals