Categorie
RA-8
Les marques,
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Analogs
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Les marques melange
No information avaliable
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Formule chimique
C24H40N8O4
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RX lien
http://www.rxlist.com/cgi/generic2/dipyrid.htm
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FDA fiche
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msds (fiche de securite des materiaux)
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Synthese de reference
FG Fischer et al., Et le brevet US. 3,031,450 (1962)
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Poids moleculaire
504.626 g/mol
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Point de fusion
163oC
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H2O Solubilite
Légèrement
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Etat
Solid
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LogP
-0.01
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Formes pharmaceutiques
Comprimés
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Indication
Pour en complément des antivitamines K dans la prévention des complications thrombo-emboliques post-opératoires du remplacement de valve cardiaque et également utilisé dans la prévention de l'angine.
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Pharmacologie
Dipyridamole, un vasodilatateur non nitrates coronaires qui inhibe également l'agrégation plaquettaire, est combiné avec d'autres médicaments anticoagulants comme la warfarine, pour prévenir la thrombose chez les patients ayant une valvulopathie ou troubles vasculaires. Le dipyridamole est également utilisé dans l'imagerie de perfusion myocardique, comme un agent antiplaquettaire, et en combinaison avec l'aspirine pour la prophylaxie course.
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Absorption
70%
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Toxicite
L'hypotension, si elle survient, est susceptible d'être de courte durée, mais un médicament vasopresseur peut être utilisé si nécessaire. La DL50 orale chez le rat est supérieure à 6000 mg / kg, tandis que chez les chiens, la DL50 orale est d'environ 400 mg / kg. DL50 = 8.4g/kg (oralement chez le rat)
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Information pour les patients
Description
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This medicine is sometimes called a "blood thinner". This medicine prevents blood clots form forming and may be given following a stroke or heart attack or for patient who have an irregular heart beat.
General Information
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This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your healthcare provider.
Proper use of this medicine
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Take this medicine exactly as directed. Do not take more or less of this medicine than prescribed. Your doctor may change the dosage of this medicine. Keep all lab appointments.
Missed Dose
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Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses.
Storage
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Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed.
Possible Side Effects
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Check with your doctor as soon as possible if you experience any of the following:
nosebleeds
excessive bleeding from cuts
bleeding from your gums
excessive bruising
discoloration of urine or stools
black tarry stools.
If you experience any of these side effects, talk to you health care provider as soon as possible, back or stomach pain, black tarry stools, blood in urine, coughing up blood, difficulty breathing, dizziness or fainting spells, heavy menstrual bleeding, n
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Organismes affectes
Les humains et autres mammifères