Categorie
Procyclidine
Les marques,
Procyclidine
Analogs
Procyclidine
Les marques melange
No information avaliable
Procyclidine
Formule chimique
C19H29NO
Procyclidine
RX lien
No information avaliable
Procyclidine
FDA fiche
Procyclidine
msds (fiche de securite des materiaux)
Procyclidine
Synthese de reference
Adamson, le brevet américain. 2.891.890 (1959 à Burroughs Wellcome)
Procyclidine
Poids moleculaire
287.44 g/mol
Procyclidine
Point de fusion
86 oC
Procyclidine
H2O Solubilite
Modérément soluble dans l'eau, ~ 30 mg / ml
Procyclidine
Etat
Solid
Procyclidine
LogP
4.37
Procyclidine
Formes pharmaceutiques
Tablet; Elixir
Procyclidine
Indication
Pour le traitement de la maladie de Parkinson (surtout d'origine médicamenteuse)
Procyclidine
Pharmacologie
Procyclidine a une action semblable à l'atropine. C'est effets antispasmodiques sont pensés pour être lié à l'obstruction des récepteurs cholinergiques centraux M1, M2 et M4. Il est utilisé pour traiter la dysfonction parkinsonisme symptomatique et extrapyramidaux causés par les antipsychotiques.
Procyclidine
Absorption
Aucune information disponible
Procyclidine
Toxicite
DL50 = 60 mg / kg (IV chez la souris)
Procyclidine
Information pour les patients
Patient Information:
Follow your doctors instructions for taking this medicine. This medicine can be taken with food or a snack,
to minimize stomach upset. As your body becomes used to the medicine, it should be taken on an empty
stomach. Talk to your doctor about the best time of day to take the medicine. For patients taking the
extended-release forms, swallow the tablet whole, do NOT CRUSH or CHEW. You may break the tablet in half
if the whole pill is too large for you to take.
This medicine can cause dizziness or drowsiness. Be cautious when driving or performing other hazardous
activities. This medicine can impair judgment. Do NOT increase your dose of this medicine without first
talking to your doctor, even if you feel that the medicine is not working.
Discuss the risks and benefits of using this medicine during pregnancy. It is unknown whether this medicine
is excreted in breast milk. DO NOT breastfeed while taking this medicine until you have talked to your
doctor or pediatrician.
Procyclidine
Organismes affectes
Les humains et autres mammifères