Categoria
Procyclidine
Nombres de marca,
Procyclidine
Analogos
Procyclidine
Marca los nombres de mezcla
No information avaliable
Procyclidine
Formula quimica
C19H29NO
Procyclidine
RX enlace
No information avaliable
Procyclidine
FDA hoja
Procyclidine
MSDS (hoja de seguridad de materiales)
Procyclidine
Sintesis de referencia
Adamson, EE.UU. Pat. 2.891.890 (1959 a Burroughs Wellcome)
Procyclidine
Peso molecular
287.44 g/mol
Procyclidine
Punto de fusion
86 oC
Procyclidine
H2O Solubilidad
Moderadamente soluble en agua, 30 mg / ml
Procyclidine
Estado
Solid
Procyclidine
LogP
4.37
Procyclidine
Formas de dosificacion
Tablet; Elixir
Procyclidine
Indicacion
Para el tratamiento de la enfermedad de Parkinson (especialmente inducida por fármacos)
Procyclidine
Farmacologia
Prociclidina tiene una acción similar a la atropina. Sus efectos antiespasmódicos se cree que está relacionada con el bloqueo del centro de receptores colinérgicos M1, M2 y M4. Se utiliza para tratar el parkinsonismo sintomático y de la disfunción extrapiramidales causadas por agentes antipsicóticos.
Procyclidine
Absorcion
No hay información disponible
Procyclidine
Toxicidad
DL50 = 60 mg / kg (IV en ratones)
Procyclidine
Informacion de Pacientes
Patient Information:
Follow your doctors instructions for taking this medicine. This medicine can be taken with food or a snack,
to minimize stomach upset. As your body becomes used to the medicine, it should be taken on an empty
stomach. Talk to your doctor about the best time of day to take the medicine. For patients taking the
extended-release forms, swallow the tablet whole, do NOT CRUSH or CHEW. You may break the tablet in half
if the whole pill is too large for you to take.
This medicine can cause dizziness or drowsiness. Be cautious when driving or performing other hazardous
activities. This medicine can impair judgment. Do NOT increase your dose of this medicine without first
talking to your doctor, even if you feel that the medicine is not working.
Discuss the risks and benefits of using this medicine during pregnancy. It is unknown whether this medicine
is excreted in breast milk. DO NOT breastfeed while taking this medicine until you have talked to your
doctor or pediatrician.
Procyclidine
Organismos afectados
Humanos y otros mamíferos