Procyclidine
Procyclidine Brand names, Procyclidine Analogs
Procyclidine Brand Names Mixture
- No information avaliable
Procyclidine Chemical_Formula
C19H29NO
Procyclidine RX_link
No information avaliable
Procyclidine fda sheet
Procyclidine msds (material safety sheet)
Procyclidine Synthesis Reference
Adamson, U.S. pat. 2,891,890 (1959 to Burroughs Wellcome)
Procyclidine Molecular Weight
287.44 g/mol
Procyclidine Melting Point
86 oC
Procyclidine H2O Solubility
Moderately soluble in water, ~ 30 mg/ml
Procyclidine State
Solid
Procyclidine LogP
4.37
Procyclidine Dosage Forms
Tablet; Elixir
Procyclidine Indication
For the treatment of Parkinson's Disease (especially drug induced)
Procyclidine Pharmacology
Procyclidine has an atropine-like action. It's antispasmodic effects are thought to be related to the blockage of central cholinergic receptors M1, M2 and M4. It is used to treat symptomatic Parkinsonism and extrapyramidal dysfunction caused by antipsychotic agents.
Procyclidine Absorption
No information avaliable
Procyclidine side effects and Toxicity
LD50=60 mg/kg (IV in mice)
Procyclidine Patient Information
Patient Information:
Follow your doctors instructions for taking this medicine. This medicine can be taken with food or a snack,
to minimize stomach upset. As your body becomes used to the medicine, it should be taken on an empty
stomach. Talk to your doctor about the best time of day to take the medicine. For patients taking the
extended-release forms, swallow the tablet whole, do NOT CRUSH or CHEW. You may break the tablet in half
if the whole pill is too large for you to take.
This medicine can cause dizziness or drowsiness. Be cautious when driving or performing other hazardous
activities. This medicine can impair judgment. Do NOT increase your dose of this medicine without first
talking to your doctor, even if you feel that the medicine is not working.
Discuss the risks and benefits of using this medicine during pregnancy. It is unknown whether this medicine
is excreted in breast milk. DO NOT breastfeed while taking this medicine until you have talked to your
doctor or pediatrician.
Follow your doctors instructions for taking this medicine. This medicine can be taken with food or a snack,
to minimize stomach upset. As your body becomes used to the medicine, it should be taken on an empty
stomach. Talk to your doctor about the best time of day to take the medicine. For patients taking the
extended-release forms, swallow the tablet whole, do NOT CRUSH or CHEW. You may break the tablet in half
if the whole pill is too large for you to take.
This medicine can cause dizziness or drowsiness. Be cautious when driving or performing other hazardous
activities. This medicine can impair judgment. Do NOT increase your dose of this medicine without first
talking to your doctor, even if you feel that the medicine is not working.
Discuss the risks and benefits of using this medicine during pregnancy. It is unknown whether this medicine
is excreted in breast milk. DO NOT breastfeed while taking this medicine until you have talked to your
doctor or pediatrician.
Procyclidine Organisms Affected
Humans and other mammals
