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Kemadrine Brand names, Kemadrine Analogs

Kemadrine Brand Names Mixture

  • No information avaliable

Kemadrine Chemical_Formula

C19H29NO

Kemadrine RX_link

No information avaliable

Kemadrine fda sheet

Kemadrine msds (material safety sheet)

Kemadrine Synthesis Reference

Adamson, U.S. pat. 2,891,890 (1959 to Burroughs Wellcome)

Kemadrine Molecular Weight

287.44 g/mol

Kemadrine Melting Point

86 oC

Kemadrine H2O Solubility

Moderately soluble in water, ~ 30 mg/ml

Kemadrine State

Solid

Kemadrine LogP

4.37

Kemadrine Dosage Forms

Tablet; Elixir

Kemadrine Indication

For the treatment of Parkinson's Disease (especially drug induced)

Kemadrine Pharmacology

Procyclidine has an atropine-like action. It's antispasmodic effects are thought to be related to the blockage of central cholinergic receptors M1, M2 and M4. It is used to treat symptomatic Parkinsonism and extrapyramidal dysfunction caused by antipsychotic agents.

Kemadrine Absorption

No information avaliable

Kemadrine side effects and Toxicity

LD50=60 mg/kg (IV in mice)

Kemadrine Patient Information

Patient Information:

Follow your doctors instructions for taking this medicine. This medicine can be taken with food or a snack,
to minimize stomach upset. As your body becomes used to the medicine, it should be taken on an empty
stomach. Talk to your doctor about the best time of day to take the medicine. For patients taking the
extended-release forms, swallow the tablet whole, do NOT CRUSH or CHEW. You may break the tablet in half
if the whole pill is too large for you to take.

This medicine can cause dizziness or drowsiness. Be cautious when driving or performing other hazardous
activities. This medicine can impair judgment. Do NOT increase your dose of this medicine without first
talking to your doctor, even if you feel that the medicine is not working.

Discuss the risks and benefits of using this medicine during pregnancy. It is unknown whether this medicine
is excreted in breast milk. DO NOT breastfeed while taking this medicine until you have talked to your
doctor or pediatrician.

Kemadrine Organisms Affected

Humans and other mammals