Lacidipine
Categorie
Lacidipine Les marques, Lacidipine Analogs
Lacidipine Les marques melange
Lacidipine Formule chimique
C22H23ClN6O
Lacidipine RX lien
http://www.rxlist.com/cgi/generic/losar.htm
Lacidipine FDA fiche
Lacidipine msds (fiche de securite des materiaux)
Lacidipine Synthese de reference
DJ Carini et al., US. 5,138,69 (1992)
Lacidipine Poids moleculaire
422.911 g/mol
Lacidipine Point de fusion
183.5-184.5 oC
Lacidipine H2O Solubilite
Lacidipine Etat
Solid
Lacidipine LogP
5.438
Lacidipine Formes pharmaceutiques
Tablet
Lacidipine Indication
Pour le traitement de l'hypertension.
Lacidipine Pharmacologie
Le losartan est le premier d'une classe d'agents antihypertenseurs, l'angiotensine II (AG II) des antagonistes du récepteur. Il est, avec ses plus agissant métabolite actif (E-3174), une sélection spécifique et Antagoniste des récepteurs AT1. Le losartan bloque l'effet vasoconstricteur et de sécrétion d'aldostérone effets de l'angiotensine II en bloquant sélectivement la liaison de l'angiotensine II au récepteur AT1 trouve dans de nombreux tissus (par exemple, le muscle lisse vasculaire, glande surrénale).
Lacidipine Absorption
Eh bien absorbée, la biodisponibilité systémique du losartan est d'environ 33%
Lacidipine Toxicite
Hypotension et une tachycardie bradycardie peut survenir à partir parasympathique (vagal), DL50 = 1000 mg / kg (par voie orale chez le rat)
Lacidipine Information pour les patients
PATIENT INFORMATION
Losartan potassium is used to treat high blood pressure. It may be used alone
or with other medications for high blood pressure. This medication should,
generally, not be used during pregnancy. If you are pregnant or considering
becoming pregnant, inform your physician immediately to discuss the risks
versus benefits. There are few side effects associated with losartan potassium.
Those most frequently reported, cough, upper respiratory infection and
dizziness, occurred no more frequently than in patients who did not take this
medication. You may take this medication with or without food. You should have
your blood pressure checked regularly
Losartan potassium is used to treat high blood pressure. It may be used alone
or with other medications for high blood pressure. This medication should,
generally, not be used during pregnancy. If you are pregnant or considering
becoming pregnant, inform your physician immediately to discuss the risks
versus benefits. There are few side effects associated with losartan potassium.
Those most frequently reported, cough, upper respiratory infection and
dizziness, occurred no more frequently than in patients who did not take this
medication. You may take this medication with or without food. You should have
your blood pressure checked regularly
Lacidipine Organismes affectes
Les humains et autres mammifères
