Lacidipine
Categoria
Lacidipine Nombres de marca, Lacidipine Analogos
Lacidipine Marca los nombres de mezcla
Lacidipine Formula quimica
C22H23ClN6O
Lacidipine RX enlace
http://www.rxlist.com/cgi/generic/losar.htm
Lacidipine FDA hoja
Lacidipine MSDS (hoja de seguridad de materiales)
Lacidipine Sintesis de referencia
DJ Carini et al., Patente de EE.UU.. 5,138,69 (1992)
Lacidipine Peso molecular
422.911 g/mol
Lacidipine Punto de fusion
183.5-184.5 oC
Lacidipine H2O Solubilidad
0,82 mg / L
Lacidipine Estado
Solid
Lacidipine LogP
5.438
Lacidipine Formas de dosificacion
Tableta
Lacidipine Indicacion
Para el tratamiento de la hipertensión.
Lacidipine Farmacologia
Losartán es el primero de una clase de fármacos antihipertensivos llamada angiotensina II (AG II) antagonistas de los receptores. Es, junto con su acción más prolongada del metabolito activo (E-3174), un selectivo y específico Antagonista de los receptores AT1. Losartán bloquea la secreción de aldosterona vasoconstrictor y efectos de la angiotensina II bloqueando selectivamente la unión de la angiotensina II al receptor AT1 encontrado en muchos tejidos (por ejemplo, el músculo liso vascular, glándula suprarrenal).
Lacidipine Absorcion
Se absorbe bien, la biodisponibilidad sistémica del losartán es de aproximadamente un 33%
Lacidipine Toxicidad
Hipotensión y taquicardia; podría ocurrir bradicardia por estimulación parasimpática (vagal), DL50 = 1000 mg / kg (por vía oral en ratas)
Lacidipine Informacion de Pacientes
PATIENT INFORMATION
Losartan potassium is used to treat high blood pressure. It may be used alone
or with other medications for high blood pressure. This medication should,
generally, not be used during pregnancy. If you are pregnant or considering
becoming pregnant, inform your physician immediately to discuss the risks
versus benefits. There are few side effects associated with losartan potassium.
Those most frequently reported, cough, upper respiratory infection and
dizziness, occurred no more frequently than in patients who did not take this
medication. You may take this medication with or without food. You should have
your blood pressure checked regularly
Losartan potassium is used to treat high blood pressure. It may be used alone
or with other medications for high blood pressure. This medication should,
generally, not be used during pregnancy. If you are pregnant or considering
becoming pregnant, inform your physician immediately to discuss the risks
versus benefits. There are few side effects associated with losartan potassium.
Those most frequently reported, cough, upper respiratory infection and
dizziness, occurred no more frequently than in patients who did not take this
medication. You may take this medication with or without food. You should have
your blood pressure checked regularly
Lacidipine Organismos afectados
Humanos y otros mamíferos
