Categoria
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Nombres de marca,
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Analogos
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Marca los nombres de mezcla
Chlor-Tripolon ND SRT (Loratadine + Pseudoephedrine Sulfate) Claritin Allergy + Sinus Extra Strength (Loratadine + Pseudoephedrine Sulfate) Liberator (Loratadine + Pseudoephedrine Sulfate)
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Formula quimica
C22H23ClN2O2
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RX enlace
http://www.rxlist.com/cgi/generic/lorat.htm
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FDA hoja
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MSDS (hoja de seguridad de materiales)
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Sintesis de referencia
FJ Villani, EE.UU. Pat. 4,282,233 (1981)
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Peso molecular
382.883 g/mol
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Punto de fusion
134-136 oC
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H2O Solubilidad
0.000011 mg / ml
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Estado
Solid
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LogP
3.646
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Formas de dosificacion
Tableta, jarabe
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Indicacion
Para el alivio de los síntomas nasales y no nasales de la rinitis alérgica estacional y para el tratamiento de la urticaria idiopática crónica en pacientes de 2 años de edad o más
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Farmacologia
Loratadina, un no sedantes H1-bloqueador con una estructura similar a la ciproheptadina y azatadina, se utiliza para tratar la rinitis alérgica estacional. A diferencia de otros bloqueadores H1, loratadina no penetra en el sistema nervioso central efectiva y tiene una baja afinidad por los receptores H1 del SNC.
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Absorcion
Absorbe rápidamente tras la administración oral (biodisponibilidad 40%)
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Toxicidad
somnolencia, taquicardia y dolor de cabeza LD50 = mg / kg (por vía oral en ratas)
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Informacion de Pacientes
Description
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This medicine is used to treat symptoms of hay fever such as runny nose,
watery eyes and sneezing. Your doctor may use antihistimines for other
conditions as well.
General Information
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This information is for educational purposes only. Not every known side
effect, adverse effect, or drug interaction is in this database. If you
have questions about your medicines, talk to your healthcare provider.
Proper use of this medicine
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For proper use of this medicine, follow the directions on the package,
unless otherwise instructed by your doctor.
Missed Dose
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If your doctor has instructed you to take this medicine regularly and you
miss a dose, take your next dose, as soon as you remember. If you are close
to your next dose, do not double up. Skip the missed dose and go back to
your regular schedule.
Storage
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Keep this medication in the container it came in, tightly closed, and out
of reach of children. Store it at room temperature and away from excess
heat and moisture (not in the bathroom). Throw away any medication that
is outdated or no longer needed.
Possible Side Effects
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Common side effects include:
dizzines
drowsiness
dry mouth
This medicine can cause excitement especially in children.
See a doctor immediately if you experience:
fast or irregular heartbeat
mental or mood changes
tightness in the chest
unusual tiredness or weakness.
While taking this medicine, if you experience, chest tightness, difficulty
in breathing or swallowing, swelling in the face or lips, go to the doctor
immediately and stop taking the medication until you have talked to your
doctor.
Warnings/Precautions
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Do NOT take this medicine with orange, apple or grapefruit juice. The levels
of this medicine in your blood may be decreased by 70%.
Overdose
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Seek medical attention immediately. For non emergencies, contact your local
or regional poison control center
Drug Interactions
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Before taking any other medications, by prescription or over-the-counter
(OTC) talk to your health care provider. Some medicines may change the way
this medicine affects your body. Also the effects of other medicines may
be increased or decreased by this medicine.
Pregnancy/Nursing
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Talk to your doctor about using this medicine during pregnancy or nursing
to discuss any possible risks to you or your baby.
More Information
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For more information about this medicine, talk to your healthcare provider
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Organismos afectados
Humanos y otros mamíferos