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Isradipine (USP) Nombres de marca, Isradipine (USP) Analogos

Isradipine (USP) Marca los nombres de mezcla

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  • Isradipine (USP) Formula quimica

    C19H21N3O5

    Isradipine (USP) RX enlace

    http://www.rxlist.com/cgi/generic2/israd.htm

    Isradipine (USP) FDA hoja

    Isradipine (USP) MSDS (hoja de seguridad de materiales)

    Isradipine_(USP) MSDS

    Isradipine (USP) Sintesis de referencia

    P. Neumann, EE.UU. Pat. 4,466,972 (1984)

    Isradipine (USP) Peso molecular

    371.387 g/mol

    Isradipine (USP) Punto de fusion

    168-170 oC

    Isradipine (USP) H2O Solubilidad

    Prácticamente insoluble (<10 mg / L a 37 ° C)

    Isradipine (USP) Estado

    Solid

    Isradipine (USP) LogP

    2.901

    Isradipine (USP) Formas de dosificacion

    Cápsulas (2,5 mg o 5 mg)

    Isradipine (USP) Indicacion

    Para el manejo de la hipertensión. Se puede utilizar solo o junto con los diuréticos tipo tiazida.

    Isradipine (USP) Farmacologia

    Isradipino, el más potente del canal del calcio agente de bloqueo de la clase dihidropiridina, es similar a la nifedipina, amlodipina, y felodipino. Se une a los canales de calcio con una alta afinidad y especificidad e inhibe el flujo de calcio en el músculo cardiaco y liso. Los efectos observados en los experimentos de mecánica in vitro y estudiado en los animales intactos y el hombre son compatibles con este mecanismo de acción y son típicos de la clase.

    Isradipine (USP) Absorcion

    Isradipina es de 90% -95% es absorbido y es sujeto a un amplio metabolismo de primer paso, resultando en una biodisponibilidad de aproximadamente el 15% -24%.

    Isradipine (USP) Toxicidad

    Los síntomas de sobredosis incluyen letargo, taquicardia sinusal e hipotensión transitoria. Letalidad significativa se observó en los ratones que recibieron dosis orales de más de 200 mg / kg y conejos que recibieron aproximadamente 50 mg / kg de isradipina. Las ratas toleraron dosis de más de 2000 mg / kg sin efectos sobre la supervivencia.

    Isradipine (USP) Informacion de Pacientes

    Description
    --------------------------------------------------------------------------------

    For those patients who have high blood pressure, and is sometime used to treat angina
    (chest pains).

    General Information
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    This information is for educational purposes only. Not every known side effect, adverse
    effect, or drug interaction is in this database. If you have questions about your medicines,
    talk to your healthcare provider.

    Proper use of this medicine
    --------------------------------------------------------------------------------

    Take this medicine exactly as directed. This medicine is normally taken once daily. It is
    taken orally and may be taken with or without food. The extended-release tablet and capsule
    should be swallowed whole. Do not chew, divide, or crush the extended-release tablet or
    capsule.


    Missed Dose
    --------------------------------------------------------------------------------

    Take your next dose as soon as you remember. If it is time for your next dose, skip the
    missed dose and go back to your regular schedule. Do not double doses.


    Storage
    --------------------------------------------------------------------------------

    Keep this medication in the container it came in, tightly closed, and out of reach of
    children. Store it at room temperature and away from excess heat and moisture. Throw away
    any medication that is outdated or no longer needed.


    Possible Side Effects
    --------------------------------------------------------------------------------

    If you experience other bothersome side effects, contact your health care provider.
    Some common side effects reported with this medicine include:
    nausea
    dizziness
    headache
    swelling


    Warnings/Precautions
    --------------------------------------------------------------------------------

    Do not stop suddenly stop this medicine without talking to your doctor.
    This medicine can cause dizziness. Use caution when operating a motor vehicle.


    Overdose
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    Seek medical attention immediately. For non emergencies, contact your local or regional
    poison control center


    Drug Interactions
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    Tell your doctor and pharmacist about all other medicines that you are taking, including
    non-prescription medicines, nutritional supplements, or herbal products.


    Pregnancy/Nursing
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    If you suspect that you may be pregnant, talk to your doctor. There are no clear answers,
    but animal studies suggest caution during pregnancy, and use should only be when risks are
    outweighed by possible benefits. For nursing mothers, it is not known if amlodipine is
    excreted in breast milk, so caution is recommended.


    More Information
    --------------------------------------------------------------------------------

    For more information about this medicine, talk to your healthcare provider.

    Isradipine (USP) Organismos afectados

    Humanos y otros mamíferos