Dynacirc CR en es it fr

Dynacirc CR Brand names, Dynacirc CR Analogs

Dynacirc CR Brand Names Mixture

  • No information avaliable

Dynacirc CR Chemical_Formula


Dynacirc CR RX_link


Dynacirc CR fda sheet

Dynacirc CR msds (material safety sheet)

Dynacirc_CR MSDS

Dynacirc CR Synthesis Reference

P. Neumann, U.S. Pat. 4,466,972 (1984)

Dynacirc CR Molecular Weight

371.387 g/mol

Dynacirc CR Melting Point

168-170 oC

Dynacirc CR H2O Solubility

Practically insoluble (< 10 mg/L at 37 °C)

Dynacirc CR State


Dynacirc CR LogP


Dynacirc CR Dosage Forms

Capsules (2.5 mg or 5 mg)

Dynacirc CR Indication

For the management of hypertension. It may be used alone or concurrently with thiazide-type diuretics.

Dynacirc CR Pharmacology

Isradipine, the most potent calcium-channel blocking agent of the dihydropyridine class, is similar to nifedipine, amlodipine, and felodipine. It binds to calcium channels with high affinity and specificity and inhibits calcium flux into cardiac and smooth muscle. The effects observed in mechanistic experiments in vitro and studied in intact animals and man are compatible with this mechanism of action and are typical of the class.

Dynacirc CR Absorption

Isradipine is 90%-95% absorbed and is subject to extensive first-pass metabolism, resulting in a bioavailability of about 15%-24%.

Dynacirc CR side effects and Toxicity

Symptoms of overdose include lethargy, sinus tachycardia, and transient hypotension. Significant lethality was observed in mice given oral doses of over 200 mg/kg and rabbits given about 50 mg/kg of isradipine. Rats tolerated doses of over 2000 mg/kg without effects on survival.

Dynacirc CR Patient Information


For those patients who have high blood pressure, and is sometime used to treat angina
(chest pains).

General Information

This information is for educational purposes only. Not every known side effect, adverse
effect, or drug interaction is in this database. If you have questions about your medicines,
talk to your healthcare provider.

Proper use of this medicine

Take this medicine exactly as directed. This medicine is normally taken once daily. It is
taken orally and may be taken with or without food. The extended-release tablet and capsule
should be swallowed whole. Do not chew, divide, or crush the extended-release tablet or

Missed Dose

Take your next dose as soon as you remember. If it is time for your next dose, skip the
missed dose and go back to your regular schedule. Do not double doses.


Keep this medication in the container it came in, tightly closed, and out of reach of
children. Store it at room temperature and away from excess heat and moisture. Throw away
any medication that is outdated or no longer needed.

Possible Side Effects

If you experience other bothersome side effects, contact your health care provider.
Some common side effects reported with this medicine include:


Do not stop suddenly stop this medicine without talking to your doctor.
This medicine can cause dizziness. Use caution when operating a motor vehicle.


Seek medical attention immediately. For non emergencies, contact your local or regional
poison control center

Drug Interactions

Tell your doctor and pharmacist about all other medicines that you are taking, including
non-prescription medicines, nutritional supplements, or herbal products.


If you suspect that you may be pregnant, talk to your doctor. There are no clear answers,
but animal studies suggest caution during pregnancy, and use should only be when risks are
outweighed by possible benefits. For nursing mothers, it is not known if amlodipine is
excreted in breast milk, so caution is recommended.

More Information

For more information about this medicine, talk to your healthcare provider.

Dynacirc CR Organisms Affected

Humans and other mammals