Dynacirc
Categoria
Dynacirc Nombres de marca, Dynacirc Analogos
Dynacirc Marca los nombres de mezcla
Dynacirc Formula quimica
C19H21N3O5
Dynacirc RX enlace
http://www.rxlist.com/cgi/generic2/israd.htm
Dynacirc FDA hoja
Dynacirc MSDS (hoja de seguridad de materiales)
Dynacirc Sintesis de referencia
P. Neumann, EE.UU. Pat. 4,466,972 (1984)
Dynacirc Peso molecular
371.387 g/mol
Dynacirc Punto de fusion
168-170 oC
Dynacirc H2O Solubilidad
Prácticamente insoluble (<10 mg / L a 37 ° C)
Dynacirc Estado
Solid
Dynacirc LogP
2.901
Dynacirc Formas de dosificacion
Cápsulas (2,5 mg o 5 mg)
Dynacirc Indicacion
Para el manejo de la hipertensión. Se puede utilizar solo o junto con los diuréticos tipo tiazida.
Dynacirc Farmacologia
Isradipino, el más potente del canal del calcio agente de bloqueo de la clase dihidropiridina, es similar a la nifedipina, amlodipina, y felodipino. Se une a los canales de calcio con una alta afinidad y especificidad e inhibe el flujo de calcio en el músculo cardiaco y liso. Los efectos observados en los experimentos de mecánica in vitro y estudiado en los animales intactos y el hombre son compatibles con este mecanismo de acción y son típicos de la clase.
Dynacirc Absorcion
Isradipina es de 90% -95% es absorbido y es sujeto a un amplio metabolismo de primer paso, resultando en una biodisponibilidad de aproximadamente el 15% -24%.
Dynacirc Toxicidad
Los síntomas de sobredosis incluyen letargo, taquicardia sinusal e hipotensión transitoria. Letalidad significativa se observó en los ratones que recibieron dosis orales de más de 200 mg / kg y conejos que recibieron aproximadamente 50 mg / kg de isradipina. Las ratas toleraron dosis de más de 2000 mg / kg sin efectos sobre la supervivencia.
Dynacirc Informacion de Pacientes
Description
--------------------------------------------------------------------------------
For those patients who have high blood pressure, and is sometime used to treat angina
(chest pains).
General Information
--------------------------------------------------------------------------------
This information is for educational purposes only. Not every known side effect, adverse
effect, or drug interaction is in this database. If you have questions about your medicines,
talk to your healthcare provider.
Proper use of this medicine
--------------------------------------------------------------------------------
Take this medicine exactly as directed. This medicine is normally taken once daily. It is
taken orally and may be taken with or without food. The extended-release tablet and capsule
should be swallowed whole. Do not chew, divide, or crush the extended-release tablet or
capsule.
Missed Dose
--------------------------------------------------------------------------------
Take your next dose as soon as you remember. If it is time for your next dose, skip the
missed dose and go back to your regular schedule. Do not double doses.
Storage
--------------------------------------------------------------------------------
Keep this medication in the container it came in, tightly closed, and out of reach of
children. Store it at room temperature and away from excess heat and moisture. Throw away
any medication that is outdated or no longer needed.
Possible Side Effects
--------------------------------------------------------------------------------
If you experience other bothersome side effects, contact your health care provider.
Some common side effects reported with this medicine include:
nausea
dizziness
headache
swelling
Warnings/Precautions
--------------------------------------------------------------------------------
Do not stop suddenly stop this medicine without talking to your doctor.
This medicine can cause dizziness. Use caution when operating a motor vehicle.
Overdose
--------------------------------------------------------------------------------
Seek medical attention immediately. For non emergencies, contact your local or regional
poison control center
Drug Interactions
--------------------------------------------------------------------------------
Tell your doctor and pharmacist about all other medicines that you are taking, including
non-prescription medicines, nutritional supplements, or herbal products.
Pregnancy/Nursing
--------------------------------------------------------------------------------
If you suspect that you may be pregnant, talk to your doctor. There are no clear answers,
but animal studies suggest caution during pregnancy, and use should only be when risks are
outweighed by possible benefits. For nursing mothers, it is not known if amlodipine is
excreted in breast milk, so caution is recommended.
More Information
--------------------------------------------------------------------------------
For more information about this medicine, talk to your healthcare provider.
--------------------------------------------------------------------------------
For those patients who have high blood pressure, and is sometime used to treat angina
(chest pains).
General Information
--------------------------------------------------------------------------------
This information is for educational purposes only. Not every known side effect, adverse
effect, or drug interaction is in this database. If you have questions about your medicines,
talk to your healthcare provider.
Proper use of this medicine
--------------------------------------------------------------------------------
Take this medicine exactly as directed. This medicine is normally taken once daily. It is
taken orally and may be taken with or without food. The extended-release tablet and capsule
should be swallowed whole. Do not chew, divide, or crush the extended-release tablet or
capsule.
Missed Dose
--------------------------------------------------------------------------------
Take your next dose as soon as you remember. If it is time for your next dose, skip the
missed dose and go back to your regular schedule. Do not double doses.
Storage
--------------------------------------------------------------------------------
Keep this medication in the container it came in, tightly closed, and out of reach of
children. Store it at room temperature and away from excess heat and moisture. Throw away
any medication that is outdated or no longer needed.
Possible Side Effects
--------------------------------------------------------------------------------
If you experience other bothersome side effects, contact your health care provider.
Some common side effects reported with this medicine include:
nausea
dizziness
headache
swelling
Warnings/Precautions
--------------------------------------------------------------------------------
Do not stop suddenly stop this medicine without talking to your doctor.
This medicine can cause dizziness. Use caution when operating a motor vehicle.
Overdose
--------------------------------------------------------------------------------
Seek medical attention immediately. For non emergencies, contact your local or regional
poison control center
Drug Interactions
--------------------------------------------------------------------------------
Tell your doctor and pharmacist about all other medicines that you are taking, including
non-prescription medicines, nutritional supplements, or herbal products.
Pregnancy/Nursing
--------------------------------------------------------------------------------
If you suspect that you may be pregnant, talk to your doctor. There are no clear answers,
but animal studies suggest caution during pregnancy, and use should only be when risks are
outweighed by possible benefits. For nursing mothers, it is not known if amlodipine is
excreted in breast milk, so caution is recommended.
More Information
--------------------------------------------------------------------------------
For more information about this medicine, talk to your healthcare provider.
Dynacirc Organismos afectados
Humanos y otros mamíferos
