Xigris (Eli Lilly
Brand names,
Xigris (Eli Lilly
Analogs
Xigris (Eli Lilly
Brand Names Mixture
Xigris (Eli Lilly
Chemical_Formula
C1786H2779N509O519S29
Xigris (Eli Lilly
RX_link
http://www.rxlist.com/cgi/generic/drotrecogin.htm
Xigris (Eli Lilly
fda sheet
Xigris (Eli Lilly
msds (material safety sheet)
Xigris (Eli Lilly
Synthesis Reference
No information avaliable
Xigris (Eli Lilly
Molecular Weight
55000
Xigris (Eli Lilly
Melting Point
No information avaliable
Xigris (Eli Lilly
H2O Solubility
No information avaliable
Xigris (Eli Lilly
State
Liquid
Xigris (Eli Lilly
LogP
-0.291
Xigris (Eli Lilly
Dosage Forms
Powder for solution
Xigris (Eli Lilly
Indication
For treatment of severe sepsis
Xigris (Eli Lilly
Pharmacology
Activated Protein C exerts an antithrombotic effect by inhibiting (cleaving) Factors Va and VIIIa. In vitro data indicate that Activated Protein C has indirect profibrinolytic activity through its ability to inhibit plasminogen activator inhibitor-1 (PAI-1) and limiting generation of activated thrombin-activatable-fibrinolysis-inhibitor. The net effect is the reduction or elimination of blood clots
Xigris (Eli Lilly
Absorption
No information avaliable
Xigris (Eli Lilly
side effects and Toxicity
No information avaliable
Xigris (Eli Lilly
Patient Information
No information avaliable
Xigris (Eli Lilly
Organisms Affected
Humans and other mammals