Anticoagulant protein C
Brand names,
Anticoagulant protein C
Analogs
Anticoagulant protein C
Brand Names Mixture
Anticoagulant protein C
Chemical_Formula
C1786H2779N509O519S29
Anticoagulant protein C
RX_link
http://www.rxlist.com/cgi/generic/drotrecogin.htm
Anticoagulant protein C
fda sheet
Anticoagulant protein C
msds (material safety sheet)
Anticoagulant protein C
Synthesis Reference
No information avaliable
Anticoagulant protein C
Molecular Weight
55000
Anticoagulant protein C
Melting Point
No information avaliable
Anticoagulant protein C
H2O Solubility
No information avaliable
Anticoagulant protein C
State
Liquid
Anticoagulant protein C
LogP
-0.291
Anticoagulant protein C
Dosage Forms
Powder for solution
Anticoagulant protein C
Indication
For treatment of severe sepsis
Anticoagulant protein C
Pharmacology
Activated Protein C exerts an antithrombotic effect by inhibiting (cleaving) Factors Va and VIIIa. In vitro data indicate that Activated Protein C has indirect profibrinolytic activity through its ability to inhibit plasminogen activator inhibitor-1 (PAI-1) and limiting generation of activated thrombin-activatable-fibrinolysis-inhibitor. The net effect is the reduction or elimination of blood clots
Anticoagulant protein C
Absorption
No information avaliable
Anticoagulant protein C
side effects and Toxicity
No information avaliable
Anticoagulant protein C
Patient Information
No information avaliable
Anticoagulant protein C
Organisms Affected
Humans and other mammals