Blood coagulation factor XIV
Brand names,
Blood coagulation factor XIV
Analogs
Blood coagulation factor XIV
Brand Names Mixture
Blood coagulation factor XIV
Chemical_Formula
C1786H2779N509O519S29
Blood coagulation factor XIV
RX_link
http://www.rxlist.com/cgi/generic/drotrecogin.htm
Blood coagulation factor XIV
fda sheet
Blood coagulation factor XIV
msds (material safety sheet)
Blood coagulation factor XIV
Synthesis Reference
No information avaliable
Blood coagulation factor XIV
Molecular Weight
55000
Blood coagulation factor XIV
Melting Point
No information avaliable
Blood coagulation factor XIV
H2O Solubility
No information avaliable
Blood coagulation factor XIV
State
Liquid
Blood coagulation factor XIV
LogP
-0.291
Blood coagulation factor XIV
Dosage Forms
Powder for solution
Blood coagulation factor XIV
Indication
For treatment of severe sepsis
Blood coagulation factor XIV
Pharmacology
Activated Protein C exerts an antithrombotic effect by inhibiting (cleaving) Factors Va and VIIIa. In vitro data indicate that Activated Protein C has indirect profibrinolytic activity through its ability to inhibit plasminogen activator inhibitor-1 (PAI-1) and limiting generation of activated thrombin-activatable-fibrinolysis-inhibitor. The net effect is the reduction or elimination of blood clots
Blood coagulation factor XIV
Absorption
No information avaliable
Blood coagulation factor XIV
side effects and Toxicity
No information avaliable
Blood coagulation factor XIV
Patient Information
No information avaliable
Blood coagulation factor XIV
Organisms Affected
Humans and other mammals