Autoprothrombin IIA
Brand names,
Autoprothrombin IIA
Analogs
Autoprothrombin IIA
Brand Names Mixture
Autoprothrombin IIA
Chemical_Formula
C1786H2779N509O519S29
Autoprothrombin IIA
RX_link
http://www.rxlist.com/cgi/generic/drotrecogin.htm
Autoprothrombin IIA
fda sheet
Autoprothrombin IIA
msds (material safety sheet)
Autoprothrombin IIA
Synthesis Reference
No information avaliable
Autoprothrombin IIA
Molecular Weight
55000
Autoprothrombin IIA
Melting Point
No information avaliable
Autoprothrombin IIA
H2O Solubility
No information avaliable
Autoprothrombin IIA
State
Liquid
Autoprothrombin IIA
LogP
-0.291
Autoprothrombin IIA
Dosage Forms
Powder for solution
Autoprothrombin IIA
Indication
For treatment of severe sepsis
Autoprothrombin IIA
Pharmacology
Activated Protein C exerts an antithrombotic effect by inhibiting (cleaving) Factors Va and VIIIa. In vitro data indicate that Activated Protein C has indirect profibrinolytic activity through its ability to inhibit plasminogen activator inhibitor-1 (PAI-1) and limiting generation of activated thrombin-activatable-fibrinolysis-inhibitor. The net effect is the reduction or elimination of blood clots
Autoprothrombin IIA
Absorption
No information avaliable
Autoprothrombin IIA
side effects and Toxicity
No information avaliable
Autoprothrombin IIA
Patient Information
No information avaliable
Autoprothrombin IIA
Organisms Affected
Humans and other mammals