Viramune
Viramune Brand names, Viramune Analogs
Viramune Brand Names Mixture
- No information avaliable
Viramune Chemical_Formula
C15H14N4O
Viramune RX_link
http://www.rxlist.com/cgi/generic2/nevira.htm
Viramune fda sheet
Viramune msds (material safety sheet)
Viramune Synthesis Reference
Hargrave, Karl D., et al.; J.Med.Chem.; 34; 7;2231-2241(1991).
Viramune Molecular Weight
266.298 g/mol
Viramune Melting Point
196.06
Viramune H2O Solubility
0.7046 mg/L
Viramune State
Solid
Viramune LogP
1.725
Viramune Dosage Forms
Tablets; Oral suspension
Viramune Indication
For use in combination with other antiretroviral drugs in the ongoing treatment of HIV-1 infection.
Viramune Pharmacology
Nevirapine is a non-nucleoside reverse transcriptase inhibitor (nNRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). HIV-2 RT and eukaryotic DNA polymerases (such as human DNA polymerases alpha, beta, or sigma) are not inhibited by nevirapine. Nevirapine is, in general, only prescribed after the immune system has declined and infections have become evident. It is always taken with at least one other HIV medication such as Retrovir or Videx. The virus can develop resistance to nevirapine if the drug is taken alone, although even if used properly, nevirapine is effective for only a limited time.
Viramune Absorption
90% (absolute bioavailability 93 ± 9%)
Viramune side effects and Toxicity
Symptoms of overdose include edema, erythema nodosum, fatigue, fever, headache, insomnia, nausea, pulmonaryinfiltrates, rash, vertigo, vomiting, and weight decrease.
Viramune Patient Information
Viramune Organisms Affected
Human immunodeficiency virus
