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NVP Brand names, NVP Analogs

NVP Brand Names Mixture

  • No information avaliable

NVP Chemical_Formula

C15H14N4O

NVP RX_link

http://www.rxlist.com/cgi/generic2/nevira.htm

NVP fda sheet

NVP FDA

NVP msds (material safety sheet)

NVP MSDS

NVP Synthesis Reference

Hargrave, Karl D., et al.; J.Med.Chem.; 34; 7;2231-2241(1991).

NVP Molecular Weight

266.298 g/mol

NVP Melting Point

196.06

NVP H2O Solubility

0.7046 mg/L

NVP State

Solid

NVP LogP

1.725

NVP Dosage Forms

Tablets; Oral suspension

NVP Indication

For use in combination with other antiretroviral drugs in the ongoing treatment of HIV-1 infection.

NVP Pharmacology

Nevirapine is a non-nucleoside reverse transcriptase inhibitor (nNRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). HIV-2 RT and eukaryotic DNA polymerases (such as human DNA polymerases alpha, beta, or sigma) are not inhibited by nevirapine. Nevirapine is, in general, only prescribed after the immune system has declined and infections have become evident. It is always taken with at least one other HIV medication such as Retrovir or Videx. The virus can develop resistance to nevirapine if the drug is taken alone, although even if used properly, nevirapine is effective for only a limited time.

NVP Absorption

90% (absolute bioavailability 93 ± 9%)

NVP side effects and Toxicity

Symptoms of overdose include edema, erythema nodosum, fatigue, fever, headache, insomnia, nausea, pulmonaryinfiltrates, rash, vertigo, vomiting, and weight decrease.

NVP Patient Information

NVP Organisms Affected

Human immunodeficiency virus