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Vardenafil Brand names, Vardenafil Analogs

Vardenafil Brand Names Mixture

  • No information avaliable

Vardenafil Chemical_Formula


Vardenafil RX_link

Vardenafil fda sheet

Vardenafil FDA

Vardenafil msds (material safety sheet)

Vardenafil Synthesis Reference

No information avaliable

Vardenafil Molecular Weight

488.604 g/mol

Vardenafil Melting Point

192 oC

Vardenafil H2O Solubility

0.11 mg/mL (HCl salt)

Vardenafil State


Vardenafil LogP

No information avaliable

Vardenafil Dosage Forms

Tablet (5, 10, and 20 mg)

Vardenafil Indication

Used for the treatment of erectile dysfunction

Vardenafil Pharmacology

Vardenafil is used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension (PAH). Part of the physiological process of erection involves the release of nitric oxide (NO) in the corpus cavernosum. This then activates the enzyme guanylate cyclase which results in increased levels of cyclic guanosine monophosphate (cGMP), leading to smooth muscle relaxation in the corpus cavernosum, resulting in increased inflow of blood and an erection. Vardenafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum. This means that, with vardenafil on board, normal sexual stimulation leads to increased levels of cGMP in the corpus cavernosum which leads to better erections. Without sexual stimulation and no activation of the NO/cGMP system, vardenafil should not cause an erection.

Vardenafil Absorption

Vardenafil is rapidly absorbed with absolute bioavailability of approximately 15%.

Vardenafil side effects and Toxicity

Symptoms of overdose include vision changes and back and muscle pain.

Vardenafil Patient Information

Vardenafil Organisms Affected

Humans and other mammals