Vanobid en es it fr

Vanobid Brand names, Vanobid Analogs

Vanobid Brand Names Mixture

  • No information avaliable

Vanobid Chemical_Formula


Vanobid RX_link

Vanobid fda sheet

Vanobid FDA

Vanobid msds (material safety sheet)

Vanobid MSDS

Vanobid Synthesis Reference

No information avaliable

Vanobid Molecular Weight

207.269 g/mol

Vanobid Melting Point

144 oC

Vanobid H2O Solubility

No information avaliable

Vanobid State


Vanobid LogP


Vanobid Dosage Forms

Topical solution (8%)

Vanobid Indication

Used as a topical treatment in immunocompetent patients with mild to moderate onychomycosis of fingernails and toenails without lunula involvement, due to Trichophyton rubrum.

Vanobid Pharmacology

Ciclopirox is a broad-spectrum antifungal medication that also has antibacterial and anti-inflammatory properties. Its main mode of action is thought to be its high affinity for trivalent cations, which inhibit essential co-factors in enzymes. Ciclopirox exhibits either fungistatic or fungicidal activity in vitro against a broad spectrum of fungal organisms, such as dermatophytes, yeasts, dimorphic fungi, eumycetes, and actinomycetes. In addition to its broad spectrum of action, ciclopirox also exerts antibacterial activity against many Gram-positive and Gram-negative bacteria. Furthermore, the anti-inflammatory effects of ciclopirox have been demonstrated in human polymorphonuclear cells, where ciclopirox has inhibited the synthesis of prostaglandin and leukotriene. Ciclopirox can also exhibit its anti-inflammatory effects by inhibiting the formation of 5-lipoxygenase and cyclooxygenase.

Vanobid Absorption

Rapidly absorbed after oral administration. Mean absorption of ciclopirox after application to nails of all twenty digits and adjacent 5 millimeters of skin once daily for 6 months in patients with dermatophytic onychomycoses was less than 5% of the applied dose. Ciclopirox olamine also penetrates into hair and through the epidermis and hair follicles into sebaceous glands and dermis.

Vanobid side effects and Toxicity

Oral LD50 in rat is >10 ml/kg. Symptoms of overexposure include drowsiness and headache.

Vanobid Patient Information

No information avaliable

Vanobid Organisms Affected

Humans, other mammals, yeast and other fungi