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Candicidin A Brand names, Candicidin A Analogs

Candicidin A Brand Names Mixture

  • No information avaliable

Candicidin A Chemical_Formula


Candicidin A RX_link

Candicidin A fda sheet

Candicidin_A FDA

Candicidin A msds (material safety sheet)

Candicidin_A MSDS

Candicidin A Synthesis Reference

No information avaliable

Candicidin A Molecular Weight

207.269 g/mol

Candicidin A Melting Point

144 oC

Candicidin A H2O Solubility

No information avaliable

Candicidin A State


Candicidin A LogP


Candicidin A Dosage Forms

Topical solution (8%)

Candicidin A Indication

Used as a topical treatment in immunocompetent patients with mild to moderate onychomycosis of fingernails and toenails without lunula involvement, due to Trichophyton rubrum.

Candicidin A Pharmacology

Ciclopirox is a broad-spectrum antifungal medication that also has antibacterial and anti-inflammatory properties. Its main mode of action is thought to be its high affinity for trivalent cations, which inhibit essential co-factors in enzymes. Ciclopirox exhibits either fungistatic or fungicidal activity in vitro against a broad spectrum of fungal organisms, such as dermatophytes, yeasts, dimorphic fungi, eumycetes, and actinomycetes. In addition to its broad spectrum of action, ciclopirox also exerts antibacterial activity against many Gram-positive and Gram-negative bacteria. Furthermore, the anti-inflammatory effects of ciclopirox have been demonstrated in human polymorphonuclear cells, where ciclopirox has inhibited the synthesis of prostaglandin and leukotriene. Ciclopirox can also exhibit its anti-inflammatory effects by inhibiting the formation of 5-lipoxygenase and cyclooxygenase.

Candicidin A Absorption

Rapidly absorbed after oral administration. Mean absorption of ciclopirox after application to nails of all twenty digits and adjacent 5 millimeters of skin once daily for 6 months in patients with dermatophytic onychomycoses was less than 5% of the applied dose. Ciclopirox olamine also penetrates into hair and through the epidermis and hair follicles into sebaceous glands and dermis.

Candicidin A side effects and Toxicity

Oral LD50 in rat is >10 ml/kg. Symptoms of overexposure include drowsiness and headache.

Candicidin A Patient Information

No information avaliable

Candicidin A Organisms Affected

Humans, other mammals, yeast and other fungi