Vallergan
Vallergan Brand names, Vallergan Analogs
- (+-)-Alimemazine
- (+-)-Trimeprazine
- Alimemazine
- Alimemazine S,S-dioxide
- Alimezine
- Bayer 1219
- Dosegran
- Doxergan
- Dysedon
- Imakol
- Levoprome
- Methylpromazine
- Oxomemazin
- Oxomemazina [INN-Spanish]
- Oxomemazine
- Oxomemazine [DCF:INN]
- Oxomemazinum [INN-Latin]
- Oxymemazine
- Panectyl
- Repeltin
- Repetin
- Temaril
- Teralen
- Theralene
- Trimeperazine
- Trimeprazine 5,5-dioxide
- Trimeprazine hemi-(+)tartrate
- Trimeprazine Tartrat
- Trimeprazine Tartrate
- Vallergan
Vallergan Brand Names Mixture
- Vanectyl-P Tablets (Prednisolone + Trimeprazine Tartrate)
Vallergan Chemical_Formula
C18H22N2S
Vallergan RX_link
No information avaliable
Vallergan fda sheet
Vallergan msds (material safety sheet)
Vallergan Synthesis Reference
No information avaliable
Vallergan Molecular Weight
298.447 g/mol
Vallergan Melting Point
68 oC
Vallergan H2O Solubility
0.942 mg/L
Vallergan State
Solid
Vallergan LogP
5.162
Vallergan Dosage Forms
Tablet (2.5 mg); Syrup (2.5 mg/5mL); Capsule(5 mg)
Vallergan Indication
Used to prevent and relieve allergic conditions which cause pruritus (itching) and urticaria (some allergic skin reactions).
Vallergan Pharmacology
Trimeprazine (also known as Alimemazine) is a tricyclic antihistamine, similar in structure to the phenothiazine antipsychotics, but differing in the ring-substitution and chain characteristics. Trimeprazine is in the same class of drugs as chlorpromazine (Thorazine) and trifluoperazine (Stelazine); however, unlike the other drugs in this class, trimeprazine is not used clinically as an anti-psychotic. It acts as an anti-histamine, a sedative, and an anti-emetic (anti-nausea). Trimeprazine is used principally as an anti-emetic, to prevent motion sickness or as an anti-histamine in combination with other medications in cough and cold preparations. Tricyclic antihistamines are also structurally-related to the tricyclic antidepressants, explaining the antihistaminergic adverse effects of these two drug classes and also the poor tolerability profile of tricyclic H1-antihistamines.
Vallergan Absorption
Well absorbed in the digestive tract.
Vallergan side effects and Toxicity
Symptoms of overdose clumsiness or unsteadiness, seizures, severe drowsiness, flushing or redness of face, hallucinations, muscle spasms (especially of neck and back), restlessness, shortness of breath, shuffling walk, tic-like (jerky) movements of head and face, trembling and shaking of hands, and insomnia.
Vallergan Patient Information
Prescriber should notify the patient to report an form of confusion, sedation, or hypotension. Inform the patient to avoid driving and other hazardous activity if drowsiness occurs. Also inform the patient to avoid alcohol and other CNS depressants while on trimeprazine.
Vallergan Organisms Affected
Humans and other mammals
