Oxomemazine
Oxomemazine Brand names, Oxomemazine Analogs
- (+-)-Alimemazine
- (+-)-Trimeprazine
- Alimemazine
- Alimemazine S,S-dioxide
- Alimezine
- Bayer 1219
- Dosegran
- Doxergan
- Dysedon
- Imakol
- Levoprome
- Methylpromazine
- Oxomemazin
- Oxomemazina [INN-Spanish]
- Oxomemazine
- Oxomemazine [DCF:INN]
- Oxomemazinum [INN-Latin]
- Oxymemazine
- Panectyl
- Repeltin
- Repetin
- Temaril
- Teralen
- Theralene
- Trimeperazine
- Trimeprazine 5,5-dioxide
- Trimeprazine hemi-(+)tartrate
- Trimeprazine Tartrat
- Trimeprazine Tartrate
- Vallergan
Oxomemazine Brand Names Mixture
- Vanectyl-P Tablets (Prednisolone + Trimeprazine Tartrate)
Oxomemazine Chemical_Formula
C18H22N2S
Oxomemazine RX_link
No information avaliable
Oxomemazine fda sheet
Oxomemazine msds (material safety sheet)
Oxomemazine Synthesis Reference
No information avaliable
Oxomemazine Molecular Weight
298.447 g/mol
Oxomemazine Melting Point
68 oC
Oxomemazine H2O Solubility
0.942 mg/L
Oxomemazine State
Solid
Oxomemazine LogP
5.162
Oxomemazine Dosage Forms
Tablet (2.5 mg); Syrup (2.5 mg/5mL); Capsule(5 mg)
Oxomemazine Indication
Used to prevent and relieve allergic conditions which cause pruritus (itching) and urticaria (some allergic skin reactions).
Oxomemazine Pharmacology
Trimeprazine (also known as Alimemazine) is a tricyclic antihistamine, similar in structure to the phenothiazine antipsychotics, but differing in the ring-substitution and chain characteristics. Trimeprazine is in the same class of drugs as chlorpromazine (Thorazine) and trifluoperazine (Stelazine); however, unlike the other drugs in this class, trimeprazine is not used clinically as an anti-psychotic. It acts as an anti-histamine, a sedative, and an anti-emetic (anti-nausea). Trimeprazine is used principally as an anti-emetic, to prevent motion sickness or as an anti-histamine in combination with other medications in cough and cold preparations. Tricyclic antihistamines are also structurally-related to the tricyclic antidepressants, explaining the antihistaminergic adverse effects of these two drug classes and also the poor tolerability profile of tricyclic H1-antihistamines.
Oxomemazine Absorption
Well absorbed in the digestive tract.
Oxomemazine side effects and Toxicity
Symptoms of overdose clumsiness or unsteadiness, seizures, severe drowsiness, flushing or redness of face, hallucinations, muscle spasms (especially of neck and back), restlessness, shortness of breath, shuffling walk, tic-like (jerky) movements of head and face, trembling and shaking of hands, and insomnia.
Oxomemazine Patient Information
Prescriber should notify the patient to report an form of confusion, sedation, or hypotension. Inform the patient to avoid driving and other hazardous activity if drowsiness occurs. Also inform the patient to avoid alcohol and other CNS depressants while on trimeprazine.
Oxomemazine Organisms Affected
Humans and other mammals
