Torasemidum (INN-Latin)

Torasemidum (INN-Latin) Brand names, Torasemidum (INN-Latin) Analogs

Torasemidum (INN-Latin) Brand Names Mixture

No information avaliable

Torasemidum (INN-Latin) Chemical_Formula

C₁₆H₂₀N₄O₃S

Torasemidum (INN-Latin) RX_link

http://www.rxlist.com/cgi/generic/demadex.htm

Torasemidum (INN-Latin) fda sheet

Torasemidum (INN-Latin) msds (material safety sheet)

Torasemidum_(INN-Latin) MSDS

Torasemidum (INN-Latin) Synthesis Reference

No information avaliable

Torasemidum (INN-Latin) Molecular Weight

348.421 g/mol

Torasemidum (INN-Latin) Melting Point

163-164 ^oC (decomposition)

Torasemidum (INN-Latin) H₂O Solubility

Soluble

Torasemidum (INN-Latin) State

Solid

Torasemidum (INN-Latin) LogP

2.404

Torasemidum (INN-Latin) Dosage Forms

Liquid; Tablet

Torasemidum (INN-Latin) Indication

For the treatment of hypertension, edema induced by congestive heart failure or renal disease, and ascites associated with hepatic disease.

Torasemidum (INN-Latin) Pharmacology

Torasemide, a monosulfonamyl loop diuretic, differs form other thiazide diuretics in that a double ring system is incorporated into its structure. Torasemide is used alone or with atenolol in the management of hypertension and edema. Micropuncture studies in animals have shown that torsemide acts from within the lumen of the thick ascending portion of the loop of Henle, where it inhibits the Na⁺/K⁺/2Cl^--carrier system.

Torasemidum (INN-Latin) Absorption

Bioavailability is approximately 80%. Serum concentration peaks after approximately 1 hour.

Torasemidum (INN-Latin) side effects and Toxicity

LD₅₀ = 5 g/kg (rat, oral), 500 mg/kg (rat, intravenous). Side effects include dizziness, headache, nausea and vomiting.

Torasemidum (INN-Latin) Patient Information