Tiagabine
Tiagabine Brand names, Tiagabine Analogs
Tiagabine Brand Names Mixture
- No information avaliable
Tiagabine Chemical_Formula
C20H25NO2S2
Tiagabine RX_link
http://www.rxlist.com/cgi/generic/gabitril.htm
Tiagabine fda sheet
Tiagabine msds (material safety sheet)
Tiagabine Synthesis Reference
No information avaliable
Tiagabine Molecular Weight
375.55 g/mol
Tiagabine Melting Point
No information avaliable
Tiagabine H2O Solubility
No information avaliable
Tiagabine State
Solid
Tiagabine LogP
3.417
Tiagabine Dosage Forms
No information avaliable
Tiagabine Indication
For the treatment of partial seizures
Tiagabine Pharmacology
Tiagabine is used primarily as an anticonvulsant for the adjunctive treatment of epilepsy. The precise mechanism by which Tiagabine exerts its antiseizure effect is unknown, although it is believed to be related to its ability to enhance the activity of gamma aminobutyric acid (GABA), the major inhibitory neurotransmitter in the central nervous system. Tiagabine binds to recognition sites associated with the GABA uptake carrier. It is thought that, by this action, Tiagabine blocks GABA uptake into presynaptic neurons, permitting more GABA to be available for receptor binding on the surfaces of post-synaptic cells.
Tiagabine Absorption
Tiagabine is nearly completely absorbed (>95%).
Tiagabine side effects and Toxicity
No information avaliable
Tiagabine Patient Information
No information avaliable
Tiagabine Organisms Affected
Humans and other mammals
