Tiagabina [Inn-Spanish]
Brand names,
Tiagabina [Inn-Spanish]
Analogs
Tiagabina [Inn-Spanish]
Brand Names Mixture
Tiagabina [Inn-Spanish]
Chemical_Formula
C20H25NO2S2
Tiagabina [Inn-Spanish]
RX_link
http://www.rxlist.com/cgi/generic/gabitril.htm
Tiagabina [Inn-Spanish]
fda sheet
Tiagabina [Inn-Spanish]
msds (material safety sheet)
Tiagabina [Inn-Spanish]
Synthesis Reference
No information avaliable
Tiagabina [Inn-Spanish]
Molecular Weight
375.55 g/mol
Tiagabina [Inn-Spanish]
Melting Point
No information avaliable
Tiagabina [Inn-Spanish]
H2O Solubility
No information avaliable
Tiagabina [Inn-Spanish]
State
Solid
Tiagabina [Inn-Spanish]
LogP
3.417
Tiagabina [Inn-Spanish]
Dosage Forms
No information avaliable
Tiagabina [Inn-Spanish]
Indication
For the treatment of partial seizures
Tiagabina [Inn-Spanish]
Pharmacology
Tiagabine is used primarily as an anticonvulsant for the adjunctive treatment of epilepsy. The precise mechanism by which Tiagabine exerts its antiseizure effect is unknown, although it is believed to be related to its ability to enhance the activity of gamma aminobutyric acid (GABA), the major inhibitory neurotransmitter in the central nervous system. Tiagabine binds to recognition sites associated with the GABA uptake carrier. It is thought that, by this action, Tiagabine blocks GABA uptake into presynaptic neurons, permitting more GABA to be available for receptor binding on the surfaces of post-synaptic cells.
Tiagabina [Inn-Spanish]
Absorption
Tiagabine is nearly completely absorbed (>95%).
Tiagabina [Inn-Spanish]
side effects and Toxicity
No information avaliable
Tiagabina [Inn-Spanish]
Patient Information
No information avaliable
Tiagabina [Inn-Spanish]
Organisms Affected
Humans and other mammals