Gabitril
Brand names,
Gabitril
Analogs
Gabitril
Brand Names Mixture
Gabitril
Chemical_Formula
C20H25NO2S2
Gabitril
RX_link
http://www.rxlist.com/cgi/generic/gabitril.htm
Gabitril
fda sheet
Gabitril
msds (material safety sheet)
Gabitril
Synthesis Reference
No information avaliable
Gabitril
Molecular Weight
375.55 g/mol
Gabitril
Melting Point
No information avaliable
Gabitril
H2O Solubility
No information avaliable
Gabitril
State
Solid
Gabitril
LogP
3.417
Gabitril
Dosage Forms
No information avaliable
Gabitril
Indication
For the treatment of partial seizures
Gabitril
Pharmacology
Tiagabine is used primarily as an anticonvulsant for the adjunctive treatment of epilepsy. The precise mechanism by which Tiagabine exerts its antiseizure effect is unknown, although it is believed to be related to its ability to enhance the activity of gamma aminobutyric acid (GABA), the major inhibitory neurotransmitter in the central nervous system. Tiagabine binds to recognition sites associated with the GABA uptake carrier. It is thought that, by this action, Tiagabine blocks GABA uptake into presynaptic neurons, permitting more GABA to be available for receptor binding on the surfaces of post-synaptic cells.
Gabitril
Absorption
Tiagabine is nearly completely absorbed (>95%).
Gabitril
side effects and Toxicity
No information avaliable
Gabitril
Patient Information
No information avaliable
Gabitril
Organisms Affected
Humans and other mammals