Tetrahydroaminocrine
Tetrahydroaminocrine Brand names, Tetrahydroaminocrine Analogs
Tetrahydroaminocrine Brand Names Mixture
- No information avaliable
Tetrahydroaminocrine Chemical_Formula
C13H14N2
Tetrahydroaminocrine RX_link
http://www.rxlist.com/cgi/generic2/tacrine.htm
Tetrahydroaminocrine fda sheet
Tetrahydroaminocrine msds (material safety sheet)
Tetrahydroaminocrine Synthesis Reference
No information avaliable
Tetrahydroaminocrine Molecular Weight
198.264 g/mol
Tetrahydroaminocrine Melting Point
183.5 oC
Tetrahydroaminocrine H2O Solubility
217 mg/L
Tetrahydroaminocrine State
Solid
Tetrahydroaminocrine LogP
2.298
Tetrahydroaminocrine Dosage Forms
No information avaliable
Tetrahydroaminocrine Indication
For the treatment of mild to moderate dementia of the Alzheimer's type.
Tetrahydroaminocrine Pharmacology
Tacrine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor. Tacrine is indicated for the treatment of mild to moderate dementia of the Alzheimer's type. Tacrine is postulated to exert its therapeutic effect by enhancing cholinergic function. This is accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. If this proposed mechanism of action is correct, tacrine's effect may lessen as the disease process advances and fewer cholinergic neurons remain functionally intact. There is no evidence that tacrine alters the course of the underlying dementing process.
Tetrahydroaminocrine Absorption
Tacrine is rapidly absorbed. Absolute bioavailability of tacrine is approximately 17 ± 13%.
Tetrahydroaminocrine side effects and Toxicity
No information avaliable
Tetrahydroaminocrine Patient Information
No information avaliable
Tetrahydroaminocrine Organisms Affected
Humans and other mammals
