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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C15H12N2O
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RX_link
http://www.rxlist.com/cgi/generic/carbam.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
Schindler, U.S. Pat. 2,948,718 (1960)
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Molecular Weight
236.269 g/mol
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Melting Point
190.2 oC
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H2O Solubility
17.7 mg/L
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State
Solid
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LogP
2.69
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Dosage Forms
Suspension; Tablet; Tablet (extended-release)
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Indication
For the treatment of epilepsy and pain associated with true trigeminal neuralgia.
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Pharmacology
Carbamazepine, an anticonvulsant structurally similar to tricyclic antidepressants, is used to treat partial seizures, tonic-clonic seizures, pain of neurologic origin such as trigeminal neuralgia, and psychiatric disorders including manic-depressive illness and aggression due to dementia.
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Absorption
No information avaliable
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side effects and Toxicity
Mild ingestions cause vomiting, drowsiness, ataxia, slurred speech, nystagmus, dystonic reactions, and hallucinations. Severe intoxications may produce coma, seizures, respiratory depression, and hypotension
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Patient Information
PATIENT INFORMATION
Carbamazepine is used for the treatment of seizures. It also is used to treat certain types of nerve pain. Inform your physican if you are pregnant or nursing. Inform your physician if you have glaucoma. Do not take this medication with a monoamine oxidase inhibitor. This medication may cause dizziness, drowsiness, or blurred vision; use caution while driving or operating hazardous machinery. Do not stop taking carbamazepine without talking with your physician. Shake the suspension well before each use. This medication should be taken with meals to avoid stomach upset. Notify your physician if you develop unexplained fever, sore throat, unusual bleeding or bruising, or yellow eyes or skin.
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Organisms Affected
Humans and other mammals